Gehlert S, Song I H, Chang C-H, Hartlage S A
Center for Interdisciplinary Health Disparities Research, The University of Chicago, Chicago, IL, USA.
Psychol Med. 2009 Jan;39(1):129-36. doi: 10.1017/S003329170800322X. Epub 2008 Mar 26.
Premenstrual dysphoric disorder (PMDD) was included as a provisional diagnostic category in the appendices of Diagnostic and Statistical Manual of Mental Disorders (DSM)-III-R (then called late luteal phase dysphoric disorder) and remained as an appendix in DSM-IV. Our study aimed to determine the prevalence of PMDD using all four DSM-IV research diagnostic criteria in a representative sample of women of reproductive age in the United States.
Data were collected in the homes of women between the ages of 13 and 55 years in two urban and two rural sites using a random sampling procedure developed by the National Opinion Research Center. Women completed daily symptom questionnaires and provided urine specimens each day for two consecutive ovulatory menstrual cycles (ovulation was estimated for women taking oral contraceptives) and were screened for psychiatric disorders by trained interviewers. Symptoms were counted toward a diagnosis of PMDD if they worsened significantly during the late luteal week during two consecutive ovulatory menstrual cycles, occurred on days in which women reported marked interference with functioning, and were not due to another mental disorder.
In the final analysis, 1246 women who had had at least one menstrual cycle and were neither naturally nor surgically menopausal nor pregnant were selected. Of the women in the study, 1.3% met criteria for the diagnosis as defined in DSM-IV.
The prevalence of PMDD is considerably lower than DSM-IV estimates and all but one of the estimates obtained from previous studies when all DSM-IV diagnostic criteria are considered. We suggest a new process for diagnosing PMDD based on our findings.
经前烦躁障碍(PMDD)在《精神疾病诊断与统计手册》(DSM)-III-R的附录中被列为临时诊断类别(当时称为黄体后期烦躁障碍),并在DSM-IV中仍保留在附录中。我们的研究旨在使用DSM-IV的所有四项研究诊断标准,在美国有代表性的育龄妇女样本中确定PMDD的患病率。
采用美国国家民意研究中心制定的随机抽样程序,在两个城市和两个农村地区13至55岁女性的家中收集数据。女性连续两个排卵月经周期每天完成症状问卷并提供尿液样本(对于服用口服避孕药的女性估计排卵情况),并由经过培训的访谈者进行精神疾病筛查。如果症状在连续两个排卵月经周期的黄体后期显著加重,出现在女性报告对功能有明显干扰的日子,且不是由另一种精神障碍引起,则计入PMDD诊断。
在最终分析中,选择了至少有一个月经周期、既非自然绝经也非手术绝经且未怀孕的1246名女性。在研究中的女性中,1.3%符合DSM-IV定义的诊断标准。
当考虑所有DSM-IV诊断标准时,PMDD的患病率远低于DSM-IV的估计值以及之前研究中除一项以外的所有估计值。基于我们的研究结果,我们建议一种诊断PMDD的新方法。