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大鼠脑中的线粒体甘油激酶活性

Mitochondrial glycerol kinase activity in rat brain.

作者信息

Tildon J T, Stevenson J H, Ozand P T

出版信息

Biochem J. 1976 Aug 1;157(2):513-6. doi: 10.1042/bj1570513.

DOI:10.1042/bj1570513
PMID:183753
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1163884/
Abstract

Glycerol kinase activity was found in the particulate fraction of rat brain homogenates predominantly associated with mitochondria. The enzyme remained bound to the particulate fraction after treatment with a variety of solubilizing agents.

摘要

在大鼠脑匀浆的微粒部分发现甘油激酶活性，其主要与线粒体相关。在用多种增溶剂处理后，该酶仍与微粒部分结合。

相似文献

1
Mitochondrial glycerol kinase activity in rat brain.大鼠脑中的线粒体甘油激酶活性
Biochem J. 1976 Aug 1;157(2):513-6. doi: 10.1042/bj1570513.
2
Binding and function of mitochondrial glycerol kinase in comparison with those of mitochondrial hexokinase.线粒体甘油激酶与线粒体己糖激酶的结合及功能比较
Arch Biochem Biophys. 1985 Feb 15;237(1):135-41. doi: 10.1016/0003-9861(85)90262-0.
3
Subcellular distribution and kinetic properties of soluble and particulate-associated bovine adrenal glycerol kinase.可溶性及颗粒相关牛肾上腺甘油激酶的亚细胞分布和动力学特性
Mol Cell Biochem. 1984 Sep;64(1):51-61. doi: 10.1007/BF00420928.
4
Glycerol kinase and dihydroxyacetone kinase in rat brain.
J Neurochem. 1976 Feb;26(2):377-85. doi: 10.1111/j.1471-4159.1976.tb04491.x.
5
The binding of glycerol kinase to the outer membrane of rat liver mitochondria: its importance in metabolic regulation.甘油激酶与大鼠肝脏线粒体外膜的结合：其在代谢调节中的重要性。
Biochem Med. 1983 Oct;30(2):231-45. doi: 10.1016/0006-2944(83)90089-3.
6
Development of enzymes of glycerol metabolism in human fetal liver.人胎儿肝脏中甘油代谢酶的发育
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7
Serum glycerol and hepatic glycerokinase activity in the carbohydrate-sensitive BHE strain of rat.碳水化合物敏感型大鼠BHE品系中的血清甘油和肝脏甘油激酶活性
Proc Soc Exp Biol Med. 1976 Oct;153(1):158-60. doi: 10.3181/00379727-153-39501.
8
[Glycerol kinase of the porcine liver. II. Postnatal development and intracellular distribution of the enzyme].[猪肝甘油激酶。II. 该酶的出生后发育及细胞内分布]
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Glycerol metabolism in higher plants: glycerol kinase.高等植物中的甘油代谢：甘油激酶
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Glycerol oxidation in rat brain: subcellular localization and kinetic characteristics.大鼠脑中甘油的氧化：亚细胞定位及动力学特征
J Neurosci Res. 1980;5(1):7-17. doi: 10.1002/jnr.490050103.

引用本文的文献

1
Conserved family of glycerol kinase loci in Drosophila melanogaster.黑腹果蝇中甘油激酶基因座的保守家族。
Mol Genet Metab. 2006 Aug;88(4):334-45. doi: 10.1016/j.ymgme.2006.01.002. Epub 2006 Mar 20.
2
The rat retina is a useful in vivo model to study membrane lipid synthesis: rates of biosynthesis of neutral glycerides and phospholipids.大鼠视网膜是研究膜脂合成（中性甘油酯和磷脂的生物合成速率）的一种有用的体内模型。
Neurochem Res. 1981 Nov;6(11):1169-78. doi: 10.1007/BF00966675.
3
Human and rat adrenal glycerol kinase: subcellular distribution and bisubstrate kinetics.人和大鼠肾上腺甘油激酶：亚细胞分布及双底物动力学
Mol Cell Biochem. 1984 Apr;62(1):43-50. doi: 10.1007/BF00230076.
4
Subcellular distribution and kinetic properties of soluble and particulate-associated bovine adrenal glycerol kinase.可溶性及颗粒相关牛肾上腺甘油激酶的亚细胞分布和动力学特性
Mol Cell Biochem. 1984 Sep;64(1):51-61. doi: 10.1007/BF00420928.
5
Competition of glycerol with other oxidizable substrates in rat brain.甘油与大鼠脑中其他可氧化底物的竞争
Biochem J. 1986 Jul 1;237(1):47-51. doi: 10.1042/bj2370047.

本文引用的文献

1
Protein measurement with the Folin phenol reagent.使用福林酚试剂进行蛋白质测定。
J Biol Chem. 1951 Nov;193(1):265-75.
2
Oxidized and reduced pyridine nucleotide levels and enzyme activities in brain and liver of niacin deficient rats.
J Neurochem. 1962 Nov-Dec;9:589-94. doi: 10.1111/j.1471-4159.1962.tb04215.x.
3
The isolation of nerve endings from brain: an electron-microscopic study of cell fragments derived by homogenization and centrifugation.从大脑中分离神经末梢：对通过匀浆和离心获得的细胞碎片进行的电子显微镜研究。
J Anat. 1962 Jan;96(Pt 1):79-88.
4
[Glycerokinase; isolation and properties of the enzyme].[甘油激酶；该酶的分离与性质]
Biochem Z. 1957;329(4):320-31.
5
A brain-infusion method for demonstrating utilization of glycerol by rabbit brain in vivo.一种用于在体内证明兔脑对甘油利用情况的脑灌注方法。
J Appl Physiol. 1967 Nov;23(5):792-7. doi: 10.1152/jappl.1967.23.5.792.
6
Glycerol as a substrate for brain metabolism.甘油作为脑代谢的底物。
Nature. 1966 Jun 25;210(5043):1334-6. doi: 10.1038/2101334a0.
7
Respiration in vitro of synaptosomes from mammalian cerebral cortex.哺乳动物大脑皮层突触体的体外呼吸作用
J Neurochem. 1969 May;16(5):675-84. doi: 10.1111/j.1471-4159.1969.tb06444.x.
8
Malate dehydrogenase (decarboxylating) (NADP) and alpha-glycerophosphate oxidase in the developing rat.
Biochim Biophys Acta. 1968 Mar 25;151(3):681-3. doi: 10.1016/0005-2744(68)90016-8.
9
Glycerol metabolism in the neonatal rat.新生大鼠的甘油代谢
Biochem J. 1970 Jul;118(3):531-6. doi: 10.1042/bj1180531.
10
The metabolism of glycerol by hypothalamic and pituitary tissues in vitro in the rat.大鼠下丘脑和垂体组织体外对甘油的代谢
Proc Soc Exp Biol Med. 1973 Jul;143(3):616-22. doi: 10.3181/00379727-143-37378.