Tichá V, Tichý M, Jansa P
Institute of Pathology, Medical Faculty, Palacký University, Olomouc, Czechoslovakia.
Acta Univ Palacki Olomuc Fac Med. 1991;130:143-55.
Histochemical properties of the mucus were studied in 48 diffuse types and 46 intestinal types of gastric carcinoma. Diffuse type was characterized by the prevalence of intracellular secretion of mucopolysaccharides with a significant involvement of sulfated ones. In the intestinal type, extracellular secretion predominated with the occurrence of pure acid mucopolysaccharides and a smaller portion of sulfated ones. The secretion of pure neutral mucopolysaccharides was minimal in both types of gastric cancer. In the intestinal type carcinomas, incomplete intestinal type IIb metaplasia was frequently found in marginal areas of the tumor.
对48例弥漫型和46例肠型胃癌的黏液进行了组织化学特性研究。弥漫型的特征是黏多糖细胞内分泌普遍存在，硫酸化黏多糖显著参与其中。在肠型中，细胞外分泌占主导，出现纯酸性黏多糖，硫酸化黏多糖的比例较小。两种类型的胃癌中纯中性黏多糖的分泌都极少。在肠型癌中，在肿瘤边缘区域经常发现不完全的肠型IIb化生。
