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震颤随深部脑刺激的时间规律性而变化。

Tremor varies as a function of the temporal regularity of deep brain stimulation.

作者信息

Birdno Merrill J, Kuncel Alexis M, Dorval Alan D, Turner Dennis A, Grill Warren M

机构信息

Biomedical Engineering, Duke University, Duke University Medical Center, Durham, North Carolina 27708-0281, USA.

出版信息

Neuroreport. 2008 Mar 26;19(5):599-602. doi: 10.1097/WNR.0b013e3282f9e45e.

Abstract

The frequency of stimulation is one of the primary factors determining the effectiveness of deep brain stimulation (DBS) in relieving tremor. DBS efficacy, however, may depend not only on the average frequency of stimulation, but also on the temporal pattern of stimulation. We conducted intraoperative measurements of the effect of temporally irregular DBS (nonconstant interpulse intervals) on tremor. As the coefficient of variation of irregular high frequency DBS trains increased, they became less effective at reducing tremor (mixed effects regression model, P<0.04). These data provide evidence that the effects of DBS are dependent not only on the average frequency of DBS, but also on the regularity of the temporal spacing of DBS pulses.

摘要

刺激频率是决定深部脑刺激(DBS)缓解震颤有效性的主要因素之一。然而,DBS的疗效可能不仅取决于平均刺激频率,还取决于刺激的时间模式。我们对时间不规则的DBS(脉冲间期不恒定)对震颤的影响进行了术中测量。随着不规则高频DBS序列变异系数的增加,它们在减轻震颤方面的效果变得更差(混合效应回归模型,P<0.04)。这些数据表明,DBS的效果不仅取决于DBS的平均频率,还取决于DBS脉冲时间间隔的规律性。

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本文引用的文献

1
Pulse-to-pulse changes in the frequency of deep brain stimulation affect tremor and modeled neuronal activity.
J Neurophysiol. 2007 Sep;98(3):1675-84. doi: 10.1152/jn.00547.2007. Epub 2007 Jul 18.
2
Amplitude- and frequency-dependent changes in neuronal regularity parallel changes in tremor With thalamic deep brain stimulation.
IEEE Trans Neural Syst Rehabil Eng. 2007 Jun;15(2):190-7. doi: 10.1109/TNSRE.2007.897004.
4
Unitary IPSPs drive precise thalamic spiking in a circuit required for learning.
Neuron. 2005 Apr 7;46(1):129-40. doi: 10.1016/j.neuron.2004.12.057.
5
Bursting as an effective relay mode in a minimal thalamic model.
J Comput Neurosci. 2005 Mar-Apr;18(2):229-43. doi: 10.1007/s10827-005-6560-5.
6
Effect of stimulation frequency on tremor suppression in essential tremor.
Mov Disord. 2004 Oct;19(10):1163-8. doi: 10.1002/mds.20231.
8
Posture-related oscillations in human cerebellar thalamus in essential tremor are enabled by voluntary motor circuits.
J Neurophysiol. 2005 Jan;93(1):117-27. doi: 10.1152/jn.00527.2004. Epub 2004 Aug 18.
9
Deep brain stimulation creates an informational lesion of the stimulated nucleus.
Neuroreport. 2004 May 19;15(7):1137-40. doi: 10.1097/00001756-200405190-00011.
10
Modulation of tremor amplitude during deep brain stimulation at different frequencies.
Brain Cogn. 2003 Nov;53(2):190-2. doi: 10.1016/s0278-2626(03)00107-6.

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