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生活方式改变与乳腺癌预后:综述

Lifestyle changes and breast cancer prognosis: a review.

作者信息

Kellen Eliane, Vansant Greet, Christiaens Marie-Rose, Neven Patrick, Van Limbergen Erik

机构信息

Universitaire Ziekenhuizen Leuven-LUCK, Kapucijnenvoer 33, 3000, Leuven, Belgium.

出版信息

Breast Cancer Res Treat. 2009 Mar;114(1):13-22. doi: 10.1007/s10549-008-9990-8. Epub 2008 Apr 4.

Abstract

OBJECTIVE

Because of its high incidence and improving survival, breast cancer is currently the most prevalent cancer in the world. We reviewed the published literature in our search for modifiable factors valuable as an adjuvant health measure to surgery, radio and systemic therapy for breast cancer.

METHODS

We included material which was identified from computerised searches of PubMed (1966 to May, 2007). Published material was restricted to prospective cohort studies and randomised clinical trials. We reviewed the literature concerning the association between physical activity, smoking, weight gain after the diagnosis, diet and prognosis.

RESULTS AND CONCLUSION

We conclude that life style changes following standard breast cancer therapy are highly recommended (although scientific evidence is still lacking for some of inconsistency regarding available data). They include physical activity, weight control, high consumption of fruit and vegetables, and a reduction of dietary fat intake.

摘要

目的

由于乳腺癌发病率高且生存率不断提高,它目前是全球最常见的癌症。我们检索了已发表的文献,以寻找对乳腺癌手术、放疗和全身治疗有辅助健康作用的可改变因素。

方法

我们纳入了通过对PubMed(1966年至2007年5月)进行计算机检索确定的资料。已发表的资料限于前瞻性队列研究和随机临床试验。我们回顾了有关体力活动、吸烟、诊断后体重增加、饮食与预后之间关联的文献。

结果与结论

我们得出结论,强烈建议在标准乳腺癌治疗后改变生活方式(尽管现有数据存在一些不一致,某些方面仍缺乏科学证据)。这些改变包括进行体力活动、控制体重、大量食用水果和蔬菜以及减少膳食脂肪摄入。

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