Blanchard Christopher M, Courneya Kerry S, Stein Kevin
Dalhousie University, Department of Medicine, QEII Health Sciences Centre, Centre for Clinical Research, 5790 University Ave, Halifax, Nova Scotia, B3H 1V7, Canada.
J Clin Oncol. 2008 May 1;26(13):2198-204. doi: 10.1200/JCO.2007.14.6217.
To examine the prevalence and clustering of physical activity (PA), fruit and vegetable consumption (5-A-Day), and smoking across six major cancer survivor groups and to identify any associations with health-related quality of life (HRQoL).
A total of 9,105 survivors of six different cancers completed a national cross-sectional survey that included the lifestyle behavior questions and the RAND-36 Health Status Inventory.
Only a minority of cancer survivors were meeting the 5-A-Day (14.8% to 19.1%) or PA (29.6% to 47.3%) recommendations, whereas most were meeting the smoking recommendation (82.6% to 91.6%). In terms of the lifestyle behavior clusters, only 5% of cancer survivors were meeting all three recommendations. Analyses of covariance generally showed higher HRQoL in survivors who were meeting versus not meeting each lifestyle behavior recommendation with the strongest associations emerging for PA. Trend analyses showed a steep positive association between the number of lifestyle behavior recommendations being met and HRQoL for breast (P < .001), prostate (P < .001), colorectal (P < .001), bladder (P < .001), uterine (P < .001), and skin melanoma (P < .001) cancer survivors.
Few cancer survivors are meeting the PA or 5-A-Day recommendations, and even fewer are meeting all three lifestyle recommendations. The association between the current lifestyle recommendations and HRQoL in cancer survivors appears to be cumulative. Interventions to increase PA and fruit and vegetable consumption and reduce smoking are warranted and may have additive effects on the HRQoL of cancer survivors.
研究身体活动（PA）、水果和蔬菜摄入量（每日5份）以及吸烟在六个主要癌症幸存者群体中的流行情况和聚集性，并确定其与健康相关生活质量（HRQoL）的任何关联。
共有9105名六种不同癌症的幸存者完成了一项全国性横断面调查，该调查包括生活方式行为问题和兰德36项健康状况量表。
只有少数癌症幸存者达到了每日5份水果和蔬菜（14.8%至19.1%）或身体活动（29.6%至47.3%）的建议标准，而大多数人达到了吸烟建议标准（82.6%至91.6%）。就生活方式行为聚类而言，只有5%的癌症幸存者达到了所有三项建议标准。协方差分析一般显示，达到与未达到每种生活方式行为建议的幸存者相比，健康相关生活质量更高，其中身体活动的关联最为显著。趋势分析显示，达到的生活方式行为建议数量与乳腺癌（P <.001）、前列腺癌（P <.001）、结直肠癌（P <.001）、膀胱癌（P <.001）、子宫癌（P <.001）和皮肤黑色素瘤（P <.001）幸存者的健康相关生活质量之间存在强烈的正相关。
很少有癌症幸存者达到身体活动或每日5份水果和蔬菜的建议标准，达到所有三项生活方式建议的人更少。目前的生活方式建议与癌症幸存者的健康相关生活质量之间的关联似乎是累积性的。有必要采取干预措施来增加身体活动和水果及蔬菜摄入量，并减少吸烟，这可能会对癌症幸存者的健康相关生活质量产生累加效应。
