侵袭内阿米巴：60赫兹磁场对其生长和分化的影响

Entamoeba invadens: influence of 60 Hz magnetic fields on growth and differentiation.

作者信息

Rodríguez-De la Fuente Abraham O, Heredia-Rojas J Antonio, Mata-Cárdenas Benito David, Vargas-Villarreal Javier, Rodríguez-Flores Laura E, Balderas-Candanosa Isaías, Alcocer-González Juan M

机构信息

Subdirección de Postgrado, Facultad de Ciencias Biológicas, UANL, Serafín Peña 909 Norte, Monterrey, Mexico.

出版信息

Exp Parasitol. 2008 Jun;119(2):202-6. doi: 10.1016/j.exppara.2008.01.006. Epub 2008 Feb 2.

DOI:10.1016/j.exppara.2008.01.006

PMID:18396281

Abstract

Exposure to extremely low-frequency (ELF) electromagnetic fields appears to result in a number of important biological changes. In the present study, we evaluated the effects of 60 Hz sinusoidal magnetic fields (MF) at magnetic flux densities of 1.0, 1.5 and 2.0 mT on growth and differentiation of the protozoan Entamoeba invadens. We demonstrated an inhibitory growth effect when trophozoite cultures were exposed to 1.5 and 2.0 mT. Furthermore, we found that there was not a synergistic effect in cultures co-exposed to MF and Metronidazole, a cytotoxic drug against amoebic cells. In addition, MF exposure inhibited the encystation process of E. invadens.

摘要

暴露于极低频（ELF）电磁场似乎会导致许多重要的生物学变化。在本研究中，我们评估了磁通密度为1.0、1.5和2.0 mT的60 Hz正弦磁场（MF）对原生动物侵袭内阿米巴生长和分化的影响。我们发现，当滋养体培养物暴露于1.5和2.0 mT的磁场时，其生长受到抑制。此外，我们发现，在同时暴露于MF和甲硝唑（一种针对阿米巴细胞的细胞毒性药物）的培养物中，不存在协同效应。另外，暴露于MF会抑制侵袭内阿米巴的包囊形成过程。