Okamoto Fumiki, Okamoto Yoshifumi, Hiraoka Takahiro, Oshika Tetsuro
Department of Ophthalmology, Institute of Clinical Medicine, University of Tsukuba, 1-1-1 Tennoudai, Tsukuba, Ibaraki, Japan.
Am J Ophthalmol. 2008 Jul;146(1):85-90. doi: 10.1016/j.ajo.2008.02.011. Epub 2008 Apr 9.
To compare the vision-related quality of life (VR QOL) after rhegmatogenous retinal detachment (RD) surgery with that of normal controls and to investigate the relationship between the VR QOL and visual function after surgery for RD.
Prospective, consecutive, comparative case series.
The 25-Item National Eye Institute Visual Function Questionnaire (VFQ-25) was self-administered by 51 RD patients at six months after surgery. Among the patients with RD, 33 underwent pars plana vitrectomy and 18 received scleral buckling. We examined the logarithm of the minimum angle of resolution (logMAR) best-corrected visual acuity (BCVA), contrast sensitivity with the CSV-1000E (Vector Vision Co, Greenville, Ohio, USA), and low-contrast visual acuity (VA) with the CSV-1000LanC10% (Vector Vision Co). From the data obtained by CSV-1000E, the area under the log contrast sensitivity function (AULCSF) was calculated. The VFQ-25 also was administered to the 46 age-matched normal controls.
The VFQ-25 composite score and the subscales associated with near activities, mental health, dependency, and peripheral vision were significantly lower in the RD group than in the normal controls (P < .05). The VFQ-25 composite score significantly correlated with AULCSF (r = 0.354; P < .05) and low-contrast VA (r = -0.475; P < 0.001), whereas there was no correlation between the VFQ-25 composite score and logMAR BCVA (r = 0.172; P = .229).
The VR QOL is significantly impaired in patients after surgery for RD. The disturbance in VR QOL was significantly associated with deterioration of postoperative contrast sensitivity.
比较孔源性视网膜脱离（RD）手术后与正常对照组的视觉相关生活质量（VR QOL），并研究RD手术后VR QOL与视觉功能之间的关系。
前瞻性、连续性、比较性病例系列研究。
51例RD患者在术后6个月自行填写25项美国国立眼科研究所视觉功能问卷（VFQ-25）。在RD患者中，33例行玻璃体切除术，18例行巩膜扣带术。我们检查了最小分辨角对数（logMAR）最佳矫正视力（BCVA）、使用CSV-1000E（美国俄亥俄州格林维尔市Vector Vision公司）测量的对比敏感度以及使用CSV-1000LanC10%（Vector Vision公司）测量的低对比度视力（VA）。根据CSV-1000E获得的数据，计算对数对比敏感度函数下的面积（AULCSF）。46名年龄匹配的正常对照者也填写了VFQ-25。
RD组的VFQ-25综合评分以及与近视力活动、心理健康、依赖和周边视力相关的子量表得分显著低于正常对照组（P < 0.05）。VFQ-25综合评分与AULCSF（r = 0.354；P < 0.05）和低对比度VA（r = -0.475；P < 0.001）显著相关，而VFQ-25综合评分与logMAR BCVA之间无相关性（r = 0.172；P = 0.229）。
RD手术后患者的VR QOL显著受损。VR QOL的紊乱与术后对比敏感度的下降显著相关。
