Best Allan, Hiatt Robert A, Norman Cameron D
Vancouver Coastal Health Research Institute, Centre for Clinical Epidemiology and Evaluation, 718, 828 West 10th Avenue, Vancouver, BC, Canada V5Z 1L8.
Patient Educ Couns. 2008 Jun;71(3):319-27. doi: 10.1016/j.pec.2008.02.013. Epub 2008 Apr 9.
This paper was prepared by the National Cancer Institute of Canada (NCIC) Working Group on Translational Research and Knowledge Transfer. The goal was to nurture common ground upon which to build a platform for translating what we know about cancer into what we do in practice and policy.
Methods included expert panels, literature review, and concept mapping, to develop a framework that built on earlier cancer control conceptualizations of communications that have guided researchers and end users.
The concept of 'knowledge integration' is used to describe the resulting refinement and the nature of evidence necessary for decision-making to at the systems level. Current evidence for knowledge integration in cancer control is presented across the levels of individual, organizational and systems level interventions and across basic, clinical and population science knowledge bases.
A systems-oriented approach to integrating evidence into action assists organizations to conduct research and policy and practice.
Practitioners can use this framework to understand the challenges of implementing and evaluating cancer control strategies.
本文由加拿大国家癌症研究所（NCIC）转化研究与知识转移工作组撰写。目标是培育共同基础，在此基础上构建一个平台，将我们对癌症的了解转化为我们在实践和政策中的行动。
方法包括专家小组、文献综述和概念映射，以开发一个基于早期癌症控制沟通概念化的框架，这些概念化指导了研究人员和最终用户。
“知识整合”的概念用于描述由此产生的细化以及系统层面决策所需证据的性质。当前癌症控制中知识整合的证据在个体、组织和系统层面干预以及基础、临床和人群科学知识库的各个层面呈现。
一种将证据整合到行动中的系统导向方法有助于组织开展研究、制定政策和实践。
从业者可以使用这个框架来理解实施和评估癌症控制策略的挑战。
