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枇杷种子提取物对大鼠实验性诱导胃损伤的胃保护活性。

Gastroprotective activity of Eriobotrya japonica seed extract on experimentally induced gastric lesions in rats.

作者信息

Yokota Junko, Takuma Daisuke, Hamada Atsuhide, Onogawa Masahide, Yoshioka Saburo, Kusunose Masahiko, Miyamura Mitsuhiko, Kyotani Shojiro, Nishioka Yutaka

机构信息

Japan Science and Technology Agency, Kohasu, Oko-cho, Nankoku, Kochi, 783-8505, Japan.

出版信息

J Nat Med. 2008 Jan;62(1):96-100. doi: 10.1007/s11418-007-0195-y. Epub 2007 Oct 2.

DOI:10.1007/s11418-007-0195-y
PMID:18404352
Abstract

The effect of Eriobotrya japonica seed extract (ESE) prepared with 70% ethanol on gastric mucosal injury was investigated. Six experimental models with different action mechanisms were used for the evaluation. Three concentrations of ESE were prepared for each model. ESE administration was initiated 14 days before induction of gastric mucosal injury, and its effect was investigated. ESE inhibited formation of gastric mucosal injury.

摘要

研究了用70%乙醇制备的枇杷种子提取物（ESE）对胃黏膜损伤的影响。使用了六种具有不同作用机制的实验模型进行评估。为每个模型制备了三种浓度的ESE。在诱导胃黏膜损伤前14天开始给予ESE，并对其效果进行研究。ESE抑制胃黏膜损伤的形成。

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本文引用的文献

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Scavenging of reactive oxygen species by Eriobotrya japonica seed extract.枇杷种子提取物对活性氧的清除作用。
Biol Pharm Bull. 2006 Mar;29(3):467-71. doi: 10.1248/bpb.29.467.
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Gastroprotective activity of Nigella sativa L oil and its constituent, thymoquinone against acute alcohol-induced gastric mucosal injury in rats.黑种草籽油及其成分百里醌对大鼠急性酒精性胃黏膜损伤的胃保护作用。
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