Vicuña Arregui Miren, Borobio Aguilar Erika, Vila Costas Juan José, Viguria Alegría M Cruz, Arrechea Irigoyen Miren, Borda Celaya Fernando, Martínez-Peñuela Vinseda José María
Servicio de Aparato Digestivo, Hospital de Navarra, Pamplona, Navarra, Spain.
Gastroenterol Hepatol. 2008 Apr;31(4):217-20. doi: 10.1157/13117905.
Gastric plasmacytoma is an infrequent form of presentation of monoclonal gammopathy that, if ulcerated, can cause upper gastrointestinal bleeding. This entity is usually localized but may progress to multiple myeloma or other forms of monoclonal gammopathy. Differential diagnosis should be performed with other monoclonal gammopathies, based on laboratory and histological criteria, as well as with other gastric tumors such as adenocarcinoma, gastrointestinal stromal tumors, neuroendocrine tumors and lymphomas. Differential diagnosis can be based on radiological and endoscopic characteristics, although definitive diagnosis will undoubtedly be based on histological study and immunohistochemical techniques. We describe the case of a male patient who underwent investigations for upper gastrointestinal bleeding and iron deficiency anemia. The final diagnosis was multiple myeloma associated with gastric plasmacytoma.
胃浆细胞瘤是单克隆丙种球蛋白病的一种罕见表现形式，若发生溃疡，可导致上消化道出血。该实体通常为局限性，但可能进展为多发性骨髓瘤或其他形式的单克隆丙种球蛋白病。应根据实验室和组织学标准，与其他单克隆丙种球蛋白病以及其他胃部肿瘤如腺癌、胃肠道间质瘤、神经内分泌肿瘤和淋巴瘤进行鉴别诊断。鉴别诊断可基于放射学和内镜特征，尽管最终诊断无疑将基于组织学研究和免疫组化技术。我们描述了一名男性患者的病例，该患者因上消化道出血和缺铁性贫血接受了检查。最终诊断为与胃浆细胞瘤相关的多发性骨髓瘤。
