Garrido Antonio, Verdejo Cristina, Márquez José Luis, Giráldez Alvaro, Trigo Claudio, Belda Ovidio
Servicio de Aparato Digestivo, Hospital Virgen del Rocío, Sevilla, Spain.
Gastroenterol Hepatol. 2008 Apr;31(4):221-4. doi: 10.1157/13117914.
Celiac disease is the most common severe food intolerance in the Western world and is due to gluten ingestion in genetically susceptible children and adults. The key treatment in these patients is a gluten-free diet, because most complications are more common when dietary compliance is poor. The most serious complication of celiac disease is the development of neoplasms (the most common of which is enteropathy-associated T-cell lymphoma). However, a number of reports have indicated an increased prevalence of ulcerative jejunitis and extraintestinal manifestations, including chronic hepatitis, fibrosing lung disease, and epilepsy syndromes. We report the case of a 53-year-old-man with long-standing diarrhea; because celiac disease was not suspected, the patient developed celiac-associated T-cell lymphoma and mesenteric panniculitis.
乳糜泻是西方世界最常见的严重食物不耐受症，是由遗传易感性儿童和成人摄入麸质引起的。这些患者的关键治疗方法是无麸质饮食，因为当饮食依从性差时，大多数并发症更为常见。乳糜泻最严重的并发症是肿瘤的发生（最常见的是肠病相关T细胞淋巴瘤）。然而，一些报告表明，溃疡性空肠炎和肠外表现的患病率有所增加，包括慢性肝炎、纤维化肺病和癫痫综合征。我们报告了一例53岁男性长期腹泻的病例；由于未怀疑乳糜泻，该患者发展为乳糜泻相关T细胞淋巴瘤和肠系膜脂膜炎。
