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[寻找失落的记忆:在一名单纯性逆行性遗忘症患者中观察到的记忆丧失与恢复机制]

[Searching for lost memory: memory loss and recovery mechanisms observed in a patient with pure retrograde amnesia].

作者信息

Antérion C Thomas, Mazzola L, Foyatier-Michel N, Laurent B

机构信息

Unité de neuropsychologie, CM2R, service de neurologie, CHU Bellevue, 25, boulevard Pasteur, 42000 Saint-Etienne, France.

出版信息

Rev Neurol (Paris). 2008 Mar;164(3):271-7. doi: 10.1016/j.neurol.2007.06.004. Epub 2008 Feb 20.

DOI:10.1016/j.neurol.2007.06.004
PMID:18405779
Abstract

We describe a patient who developed acute reversible amnesia characterized by impaired recollection of past events with preserved anterograde memory. This occurred after a mild head trauma and in the context of occupational stress. Isolated retrograde amnesia affected autobiographical memory (with lost of identity lasting a few days) and semantic knowledge. Isolated retrograde amnesia subsided for nine months. The patient was no longer able to access to his memories, which did not seem completely lost. Some answers to tests concerning historical events were better than those given at random; his answers to a TV quiz were automatic or he exhibited temporal transfer phenomena (ecmnesia). Gradual, progressive, irregular and spontaneous or "flash" recovery, which was also facilitated by dreams, associations or contextual clues. The persistent and vivid familiarity of the retrieved memories are reported here together with the organization of long-term memory and the clinical and neuropsychological traits of functional isolated retrograde amnesia.

摘要

我们描述了一名患者,其出现急性可逆性失忆,特征为对过去事件的回忆受损而顺行性记忆保留。这发生在轻度头部创伤后且处于职业压力背景下。孤立性逆行性失忆影响了自传体记忆(身份丧失持续数天)和语义知识。孤立性逆行性失忆消退了九个月。患者不再能够获取其记忆,这些记忆似乎并未完全丧失。关于历史事件测试的一些回答比随机给出的回答要好;他对电视问答节目的回答是自动的,或者他表现出时间转移现象(错构症)。逐渐、渐进、不规则且自发或“突发”的恢复,梦境、联想或情境线索也促进了这种恢复。本文报告了所检索记忆的持续且生动的熟悉感,以及长期记忆的组织情况和功能性孤立性逆行性失忆的临床及神经心理学特征。

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