Bensamoun Sabine F, Glaser Kevin J, Ringleb Stacie I, Chen Qingshan, Ehman Richard L, An Kai-Nan
Biomechanics Laboratory, Division of Orthopedic Research, Mayo Clinic College of Medicine, Rochester, Minnesota 55905, USA.
J Magn Reson Imaging. 2008 May;27(5):1083-8. doi: 10.1002/jmri.21307.
To demonstrate the feasibility of 1D MR elastography (MRE) to rapidly assess skeletal muscle stiffness in vivo.
Shear waves were induced in the vastus medialis muscle (VM) using a pneumatic driver at 90 Hz and 2D MRE data were collected. Spatially selective excitations were used to produce 1D projections of MRE data oriented along the direction of propagating waves in the muscle. Data were collected with the thigh muscles relaxed and contracted at 20% maximum voluntary contraction (MVC) and the knee flexed at 30 degrees .
The muscle stiffness measured at rest and in contraction with 1D MRE was 3.69 +/- 0.80 kPa and 9.52 +/- 2.74 kPa, respectively, and 4.36 +/- 0.98 kPa and 9.22 +/- 1.29 kPa, respectively, with the 2D MRE technique.
Muscle stiffness measured using 1D MRE was in agreement with 2D MRE while reducing the scan time by a factor of 4.
证明一维磁共振弹性成像(MRE)在体内快速评估骨骼肌僵硬度的可行性。
使用气动驱动器以90Hz在股内侧肌(VM)中诱导剪切波,并收集二维MRE数据。采用空间选择性激发来生成沿肌肉中传播波方向的MRE数据的一维投影。在大腿肌肉放松、以最大自主收缩(MVC)的20%收缩且膝关节屈曲30度的状态下收集数据。
使用一维MRE在静息和收缩状态下测得的肌肉僵硬度分别为3.69±0.80kPa和9.52±2.74kPa,而使用二维MRE技术测得的分别为4.36±0.98kPa和9.22±1.29kPa。
使用一维MRE测得的肌肉僵硬度与二维MRE一致,同时扫描时间减少了四分之一。