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SUN队列研究中的身体活动、久坐指数与精神障碍

Physical activity, sedentary index, and mental disorders in the SUN cohort study.

作者信息

Sanchez-Villegas Almudena, Ara Ignacio, Guillén-Grima Francisco, Bes-Rastrollo Maira, Varo-Cenarruzabeitia Jose Javier, Martínez-González Miguel A

机构信息

Department of Clinical Sciences, University of Las Palmas de Gran Canaria, Las Palmas de Gran Canaria, Spain.

出版信息

Med Sci Sports Exerc. 2008 May;40(5):827-34. doi: 10.1249/MSS.0b013e31816348b9.

Abstract

PURPOSE

There is evidence to suggest a beneficial effect of physical activity on several mental disorders.

METHODS

The study aim was to assess the association between low physical activity during leisure time (or sedentary lifestyles) and the incidence of mental disorders in 10,381 participants, from a Spanish dynamic prospective cohort of university graduates followed up for 6 yr (the SUN study). The baseline assessment included a validated questionnaire on physical activity during leisure-time and sedentary activities. A subject was classified as an incident case of mental disorder if he or she reported a physician diagnosis of depression, anxiety or stress, and/or the use of antidepressant medication or tranquilizers in at least one of the follow-up questionnaires.

RESULTS

The odds ratios (OR) and 95% confidence intervals (CI) of a mental disorder for successive levels of leisure-time physical activity were 1 (reference), 1.00 (0.81, 1.23), 0.99 (0.81, 1.21), 0.72 (0.58, 0.89), and 0.81 (0.65, 1.00) (P for trend: < 0.01). The OR for subjects who spent more than 42 h.wk(-1) watching television and/or using the computer was 1.31 (95% CI = 1.01, 1.68) as compared with those spending less than 10.5 h.wk(-1).

CONCLUSION

Our findings suggest a joint association of leisure-time physical activity and sedentary behavior on the incidence of mental disorders.

摘要

目的

有证据表明体育活动对几种精神障碍有有益影响。

方法

本研究旨在评估10381名参与者休闲时间低体育活动(或久坐生活方式)与精神障碍发病率之间的关联,这些参与者来自西班牙一个对大学毕业生进行了6年随访的动态前瞻性队列(SUN研究)。基线评估包括一份关于休闲时间体育活动和久坐活动的有效问卷。如果一名受试者在至少一份随访问卷中报告医生诊断为抑郁症、焦虑症或压力症,和/或使用抗抑郁药物或镇静剂,则被分类为精神障碍的发病病例。

结果

连续休闲时间体育活动水平下精神障碍的优势比(OR)和95%置信区间(CI)分别为1(参考值)、1.00(0.81,1.23))、0.99(0.81,1.21)、0.72(0.58,0.89)和0.81(0.65,1.00)(趋势P值:<0.01)。与每周看电视和/或使用电脑少于10.5小时的受试者相比,每周花费超过42小时看电视和/或使用电脑的受试者的OR为1.31(95%CI = 1.01,1.68)。

结论

我们的研究结果表明,休闲时间体育活动和久坐行为与精神障碍发病率存在联合关联。

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