Herrero Miguel, Ibañez Elena, Cifuentes Alejandro
Institute of Industrial Fermentations, Madrid, Spain.
Electrophoresis. 2008 May;29(10):2148-60. doi: 10.1002/elps.200700404.
In the present work, an exhaustive review of the main developments and applications of CE-MS for peptide analysis is given. This review includes the use of different CE separation modes, MS analyzers, capillary coatings, preconcentration techniques, on-chip applications as well as other different multidimensional strategies for peptide analysis. Key applications are critically discussed and relevant works published from January 2000 to May 2007 are summarized including information concerning the type of sample, CE-MS parameters as well as some figures of merit of the different CE-MS procedures developed for peptide analysis and peptidomics.
在本工作中，对毛细管电泳-质谱联用技术用于肽分析的主要进展和应用进行了详尽综述。该综述涵盖了不同的毛细管电泳分离模式、质谱分析仪、毛细管涂层、预浓缩技术、芯片上的应用以及用于肽分析的其他不同多维策略。对关键应用进行了批判性讨论，并总结了2000年1月至2007年5月发表的相关文献，包括有关样品类型、毛细管电泳-质谱联用参数以及为肽分析和肽组学开发的不同毛细管电泳-质谱联用程序的一些性能指标的信息。
