Brodziak-Dopierała Barbara, Kwapuliński Jerzy, Rzepka Jerzy, Nogaj Ewa, Bogunia Mariusz, Ahnert Bozena
Katedra i Zakład Toksykologii Slaskiego, Uniwersytetu Medycznego w Katowicach.
Przegl Lek. 2007;64(10):720-2.
The smoking tobacco makes the negative influence on state of osseous tissue, many research shows, that the smoking tobacco states the factor of risk of appearance of osteoporosis. The aim of this study was determined of occurrence of 12 metals in separate parts and profiles of femur head in three studied groups: smoker persons, non-smoker and smoker in past. Human femur heads were obtained from people living in Upper Silesia cities in Poland during endoprosthetoplasty of coxa. The femur heads were cut into 5 cross-sections A-E using a stabilizing device provided with a fixed and a movable part maintained at a 12 degrees angle. As the next step, fragments of articular cartilage, cortical bone and trabecular bone were sectioned off from the cross-sections. In smoker group the large content of chrome of, nickel, zinc pays back attention. In case of individual parts of femur head notice, that the largest place in articular cartilage has accumulating metals. The largest contents of metals were observed in the external sections A and E.
许多研究表明,吸烟会对骨组织状态产生负面影响,吸烟是骨质疏松症出现风险的因素。本研究的目的是确定在三个研究组(吸烟者、非吸烟者和既往吸烟者)股骨头的不同部位和剖面中12种金属的含量。人类股骨头取自波兰上西里西亚城市接受髋关节置换术的患者。使用配有固定部分和活动部分且保持12度角的稳定装置,将股骨头切成5个横截面A-E。接下来,从横截面切下关节软骨、皮质骨和小梁骨碎片。在吸烟组中,铬、镍、锌的含量较高,值得关注。在股骨头的各个部位发现,关节软骨中金属积累最多。在外部横截面A和E中观察到金属含量最高。