钙、镁、磷、氟和铅对骨组织的影响。
The Effects of Calcium, Magnesium, Phosphorus, Fluoride, and Lead on Bone Tissue.
机构信息
Department of Medical Rehabilitation and Clinical Physiotherapy, Pomeranian Medical University in Szczecin, Żołnierska 54, 71-210 Szczecin, Poland.
Department of Biology and Medical Parasitology, Pomeranian Medical University in Szczecin, Powstańców Wielkopolskich 72, 70-111 Szczecin, Poland.
出版信息
Biomolecules. 2021 Mar 28;11(4):506. doi: 10.3390/biom11040506.
Abstract
Bones are metabolically active organs. Their reconstruction is crucial for the proper functioning of the skeletal system during bone growth and remodeling, fracture healing, and maintaining calcium-phosphorus homeostasis. The bone metabolism and tissue properties are influenced by trace elements that may act either indirectly through the regulation of macromineral metabolism, or directly by affecting osteoblast and osteoclast proliferation or activity, or through becoming part of the bone mineral matrix. This study analyzes the skeletal impact of macroelements (calcium, magnesium, phosphorus), microelements (fluorine), and heavy metals (lead), and discusses the concentration of each of these elements in the various bone tissues.
摘要
骨头是代谢活跃的器官。它们的重建对于骨骼系统在骨骼生长和重塑、骨折愈合以及维持钙磷平衡期间的正常功能至关重要。微量元素会影响骨骼代谢和组织特性，其作用方式既可以是通过调节宏量矿物质代谢间接影响，也可以是通过直接影响成骨细胞和破骨细胞的增殖或活性来影响，或者通过成为骨矿物质基质的一部分来影响。本研究分析了常量元素（钙、镁、磷）、微量元素（氟）和重金属（铅）对骨骼的影响，并讨论了这些元素在各种骨组织中的浓度。
相似文献
1
The Effects of Calcium, Magnesium, Phosphorus, Fluoride, and Lead on Bone Tissue.钙、镁、磷、氟和铅对骨组织的影响。
Biomolecules. 2021 Mar 28;11(4):506. doi: 10.3390/biom11040506.
2
Effects of excess calcium on a fluoride-magnesium interrelationship in chicks.过量钙对雏鸡氟-镁相互关系的影响。
J Nutr. 1972 Dec;102(12):1699-707. doi: 10.1093/jn/102.12.1699.
3
[Evaluation of fatty acid levels and selected bioelements in femoral bones of chicks depending on age].[根据年龄评估雏鸡股骨中的脂肪酸水平和选定生物元素]
Ann Acad Med Stetin. 2002;48:45-58.
4
Calcium, magnesium and phosphorus in experimental tumors: effects of the age of the tumor.实验性肿瘤中的钙、镁和磷：肿瘤年龄的影响
Z Krebsforsch Klin Onkol Cancer Res Clin Oncol. 1974;81(2):109-18. doi: 10.1007/BF00304151.
5
6
Weight loss alters organ concentrations and contents of lead and some essential divalent metals in rats previously exposed to lead.体重减轻会改变先前接触过铅的大鼠体内铅及一些必需二价金属的器官浓度和含量。
J Nutr. 1996 Jan;126(1):317-23. doi: 10.1093/jn/126.1.317.
7
Effect of fluoride on bone formation and strength in Japanese quail.氟对日本鹌鹑骨骼形成和强度的影响。
J Nutr. 1973 Oct;103(10):1431-40. doi: 10.1093/jn/103.10.1431.
8
Toxic and essential elements in bone--a review.骨骼中的有毒元素与必需元素——综述
J Anim Sci. 1979 Aug;49(2):482-97. doi: 10.2527/jas1979.492482x.
9
[Mineral elements content in smoked fish].[烟熏鱼中的矿物质元素含量]
Rocz Panstw Zakl Hig. 2008;59(2):187-96.
引用本文的文献
1
ONMR: an orthopedic and nutritional Mendelian randomization database.ONMR：一个骨科与营养孟德尔随机化数据库。
NPJ Sci Food. 2025 Sep 1;9(1):190. doi: 10.1038/s41538-025-00562-0.
2
Preschoolers in severely food insecure Guatemalan Mayan households consume a monotonous grain-based diet.危地马拉玛雅家庭中面临严重粮食不安全问题的学龄前儿童食用以谷物为主的单一饮食。
BMC Public Health. 2025 Aug 19;25(1):2836. doi: 10.1186/s12889-025-24111-2.
3
Bone Health in Children and Adolescents with Type 1 Diabetes: Optimizing Bone Accrual and Preventing Fractures.1型糖尿病儿童和青少年的骨骼健康：优化骨质积累与预防骨折
Nutrients. 2025 Jul 23;17(15):2400. doi: 10.3390/nu17152400.
4
Strategic incorporation of metal ions in bone regenerative scaffolds: multifunctional platforms for advancing osteogenesis.金属离子在骨再生支架中的策略性整合：促进骨生成的多功能平台
Regen Biomater. 2025 Jul 2;12:rbaf068. doi: 10.1093/rb/rbaf068. eCollection 2025.
5
Assessment of Trace and Macro Elements in Medicinal Plants: Implications for Safety and Phytoremediation.药用植物中微量元素和常量元素的评估：对安全性和植物修复的影响
Biol Trace Elem Res. 2025 Jul 2. doi: 10.1007/s12011-025-04714-x.
6
The Screening and Correlation of Trace Elements in the Blood and Urine of School-Aged Children (5-12 Years): A Pilot Biomonitoring Study.学龄儿童（5至12岁）血液和尿液中微量元素的筛查与相关性：一项初步生物监测研究
Toxics. 2025 May 25;13(6):431. doi: 10.3390/toxics13060431.
7
Predictive value of Hounsfield units and vertebral bone quality on cage subsidence in oblique lateral interbody fusion with bilateral posterior fixation.在双侧后路固定的斜外侧椎间融合术中，Hounsfield单位和椎体骨质量对椎间融合器沉降的预测价值。
J Orthop Surg Res. 2025 Jun 16;20(1):588. doi: 10.1186/s13018-025-06016-3.
8
Can supplements with prebiotic fibres positively influence bone health in type 2 diabetes? Insights from a randomised controlled crossover trial.含益生元纤维的补充剂能否对2型糖尿病患者的骨骼健康产生积极影响？一项随机对照交叉试验的见解。
Arch Osteoporos. 2025 Jun 5;20(1):71. doi: 10.1007/s11657-025-01556-x.
9
Harnessing mushrooms for poultry nutrition: Boosting health, immunity, and productivity.利用蘑菇促进家禽营养：增强健康、免疫力和生产力。
Poult Sci. 2025 Apr 28;104(8):105223. doi: 10.1016/j.psj.2025.105223.
10
Findings of preoperative patient risk factors to predict dislocation following total hip arthroplasty.预测全髋关节置换术后脱位的术前患者风险因素研究结果。
Front Cell Dev Biol. 2025 May 15;13:1601997. doi: 10.3389/fcell.2025.1601997. eCollection 2025.
本文引用的文献
1
Selenium and bone health: a protocol for a systematic review and meta-analysis.硒与骨骼健康：一项系统评价与荟萃分析方案
BMJ Open. 2020 Oct 26;10(10):e036612. doi: 10.1136/bmjopen-2019-036612.
2
Lead Toxicity and Pollution in Poland.波兰的铅毒性与污染。
Int J Environ Res Public Health. 2020 Jun 18;17(12):4385. doi: 10.3390/ijerph17124385.
3
Identification of osteoclast-osteoblast coupling factors in humans reveals links between bone and energy metabolism.鉴定人类破骨细胞-成骨细胞偶联因子揭示了骨骼与能量代谢之间的联系。
Nat Commun. 2020 Jan 7;11(1):87. doi: 10.1038/s41467-019-14003-6.
4
The heavy metals lead and cadmium are cytotoxic to human bone osteoblasts via induction of redox stress.重金属铅和镉通过诱导氧化应激对人成骨细胞产生细胞毒性。
PLoS One. 2019 Nov 22;14(11):e0225341. doi: 10.1371/journal.pone.0225341. eCollection 2019.
5
Fluorine-contained hydroxyapatite suppresses bone resorption through inhibiting osteoclasts differentiation and function in vitro and in vivo.含氟羟基磷灰石通过体外和体内抑制破骨细胞分化和功能来抑制骨吸收。
Cell Prolif. 2019 May;52(3):e12613. doi: 10.1111/cpr.12613. Epub 2019 Apr 10.
6
Osteocalcin-A Versatile Bone-Derived Hormone.骨钙素-A：一种多功能的骨源性激素。
Front Endocrinol (Lausanne). 2019 Jan 10;9:794. doi: 10.3389/fendo.2018.00794. eCollection 2018.
7
A Review of Metal Exposure and Its Effects on Bone Health.金属暴露及其对骨骼健康影响的综述
J Toxicol. 2018 Dec 23;2018:4854152. doi: 10.1155/2018/4854152. eCollection 2018.
8
The Impact of Trace Minerals on Bone Metabolism.微量元素对骨骼代谢的影响。
Biol Trace Elem Res. 2019 Mar;188(1):26-34. doi: 10.1007/s12011-018-1583-8. Epub 2018 Nov 23.
9
Calcium, magnesium, zinc and lead concentrations in the structures forming knee joint in patients with osteoarthritis.骨关节炎患者膝关节结构中钙、镁、锌和铅的浓度。
J Trace Elem Med Biol. 2018 Dec;50:409-414. doi: 10.1016/j.jtemb.2018.08.007. Epub 2018 Aug 29.
10
Urban and rural area differences in the interaction between oxidative process elements in human femoral bone.城乡地区人体股骨骨中氧化过程元素相互作用的差异。
Environ Sci Pollut Res Int. 2018 Oct;25(30):30475-30487. doi: 10.1007/s11356-018-3053-4. Epub 2018 Aug 30.
Zotero 插件