Freeman Brian J C, Mehdian Roshana
The Centre for Spinal Studies and Surgery, Nottingham University Hospitals NHS Trust, Queen's Medical Centre Campus, Nottingham NG7 2UH, UK.
Curr Pain Headache Rep. 2008 Jan;12(1):14-21. doi: 10.1007/s11916-008-0004-7.
Over the past decade, there has been a surge of minimally invasive techniques aimed at treating both discogenic low back pain (LBP) and radicular pain. This article assesses the current evidence for three such treatments: intradiscal electrothermal therapy (IDET), percutaneous discectomy, and nucleoplasty. An electronic search of the literature carried out using the Cochrane Library database (2007) and Medline (1966-2007) identified 77 references relating to IDET, 363 to percutaneous discectomy, and 36 to nucleoplasty. Two randomized controlled trials (RCTs) assessed the effectiveness of IDET; one demonstrated a positive effect on pain severity only, whereas the other demonstrated no substantial benefit. Other RCTs show that percutaneous intradiscal radiofrequency thermocoagulation is ineffective for the treatment of discogenic LBP. Trials of automated percutaneous discectomy suggest that clinical outcomes after treatment are at best fair and often worse when compared with microdiscectomy. There are no published RCTs assessing Coblation (ArthroCare Spine, Stockholm, Sweden) technology.
在过去十年中,旨在治疗椎间盘源性下腰痛(LBP)和神经根性疼痛的微创技术激增。本文评估了三种此类治疗方法的现有证据:椎间盘内电热疗法(IDET)、经皮椎间盘切除术和髓核成形术。使用Cochrane图书馆数据库(2007年)和Medline(1966 - 2007年)对文献进行的电子检索发现,与IDET相关的参考文献有77篇,与经皮椎间盘切除术相关的有363篇,与髓核成形术相关的有36篇。两项随机对照试验(RCT)评估了IDET的有效性;一项仅表明对疼痛严重程度有积极影响,而另一项则未显示出实质性益处。其他RCT表明,经皮椎间盘内射频热凝术对治疗椎间盘源性LBP无效。自动经皮椎间盘切除术的试验表明,与显微椎间盘切除术相比,治疗后的临床结果充其量只是一般,而且往往更差。目前尚无评估低温等离子消融术(ArthroCare Spine,瑞典斯德哥尔摩)技术的已发表RCT。