Coleman Anne Louise
Department of Ophthalmology, Jules Stein Eye Institute, David Geffen School of Medicine, University of California, Los Angeles, USA.
Trans Am Ophthalmol Soc. 2007;105:312-29.
To determine the sources of binocular visual field loss most strongly associated with falls in a cohort of older women.
In the Study of Osteoporotic Fractures, women with severe binocular visual field loss had an increased risk of two or more falls during the 12 months following the eye examination. The lens and fundus photographs of the 422 women with severe binocular visual field loss, plus a random sample of 141 white women with no, mild, or moderate binocular visual field loss--47 white women with no binocular visual field loss, 46 white women with mild binocular visual field loss, and 48 white women with moderate binocular visual field loss--were evaluated for lens opacities, glaucomatous optic nerve damage, age-related macular degeneration, and diabetic retinopathy.
Eighty-four percent of the women with severe binocular visual field loss had ocular disease in one or both eyes. Bilateral cataracts and glaucomatous optic nerve damage were the most common sources of this severe binocular visual field loss. Approximately 15.2% of women had no evidence of lens opacities, glaucomatous optic nerve damage, age-related macular degeneration, or diabetic retinopathy.
Severe binocular visual field loss due primarily to cataracts, glaucoma, and age-related macular degeneration explains 33.3% of the falls among women who fell frequently. Because binocular visual field loss may be treatable and/or preventable, screening programs for binocular visual field loss and subsequent referral for intervention and treatment are recommended as a strategy for preventing falls among the elderly.
确定在一组老年女性中与跌倒最密切相关的双眼视野缺损的来源。
在骨质疏松性骨折研究中,患有严重双眼视野缺损的女性在眼科检查后的12个月内发生两次或更多次跌倒的风险增加。对422名患有严重双眼视野缺损的女性以及141名无、轻度或中度双眼视野缺损的白人女性(47名无双眼视野缺损的白人女性、46名轻度双眼视野缺损的白人女性和48名中度双眼视野缺损的白人女性)的晶状体和眼底照片进行评估,以检查晶状体混浊、青光眼性视神经损伤、年龄相关性黄斑变性和糖尿病性视网膜病变。
84%患有严重双眼视野缺损的女性一只或两只眼睛患有眼部疾病。双侧白内障和青光眼性视神经损伤是这种严重双眼视野缺损最常见的来源。约15.2%的女性没有晶状体混浊、青光眼性视神经损伤、年龄相关性黄斑变性或糖尿病性视网膜病变的证据。
主要由白内障、青光眼和年龄相关性黄斑变性导致的严重双眼视野缺损解释了频繁跌倒女性中33.3%的跌倒情况。由于双眼视野缺损可能是可治疗和/或可预防的,建议开展双眼视野缺损筛查项目,并随后转诊进行干预和治疗,作为预防老年人跌倒的一种策略。