Jules Stein Eye Institute and the Department of Ophthalmology, David Geffen School of Medicine at University of California-Los Angeles, 100 Stein Plaza, Los Angeles, CA 90095-7004, USA.
Am J Ophthalmol. 2010 Feb;149(2):330-40. doi: 10.1016/j.ajo.2009.09.008.
To test the reliability and validity of questionnaires shortened from the National Eye Institute 25-item Vision Function Questionnaire (NEI VFQ-25).
Cross-sectional, multicenter cohort study.
Reliability was assessed by Cronbach alpha coefficients. Validity was evaluated by studying the association of vision-targeted quality-of-life composite scores with objective visual function measurements. A total of 5482 women between the ages of 65 and 100 years participated in the year-10 clinic visit in the Study of Osteoporotic Fractures (SOF). A total of 3631 women with complete data were included in the visual acuity (VA) and visual field (VF) analyses of the 9-item NEI VFQ (NEI VFQ-9), which is defined for those who care to drive, and a total of 5311 women with complete data were included in the VA and VF in the analyses of the 8-item NEI VFQ (NEI VFQ-8). To assess differences in prevalent eye diseases, which were ascertained for a random sample of SOF participants, 853 and 1237 women were included in the NEI VFQ-9 and the NEI VFQ-8 analyses, respectively.
The Cronbach alpha coefficient for the NEI VFQ-9 scale was 0.83, and that of the NEI VFQ-8 was 0.84. Using both questionnaires, women with VA worse than 20/40 had lower composite scores compared with those with VA of 20/40 or better (P < .001). Participants with mild, moderate, and severe binocular VF loss had lower composite scores compared with those with no binocular VF loss (P < .001). Compared with women without chronic eye diseases in both eyes, women with at least 1 chronic eye disease in at least 1 eye had lower composite scores.
Both questionnaires showed high reliability across items and validity with respect to clinical markers of eye disease. Future research should compare the properties of these shortened surveys with those of the NEI VFQ-25.
测试从国家眼科研究所 25 项视力功能问卷(NEI VFQ-25)中缩短的问卷的可靠性和有效性。
横断面、多中心队列研究。
采用 Cronbach α 系数评估信度。通过研究与目标视觉功能测量相关的视力导向生活质量综合评分来评估有效性。共有 5482 名年龄在 65 至 100 岁之间的女性参加了骨质疏松性骨折研究(SOF)的第 10 年临床访视。共有 3631 名女性的数据完整,纳入了针对有驾驶意愿人群的 9 项 NEI VFQ(NEI VFQ-9)的视力(VA)和视野(VF)分析,共有 5311 名女性的数据完整,纳入了针对所有人群的 8 项 NEI VFQ(NEI VFQ-8)的 VA 和 VF 分析。为了评估 SOF 参与者随机样本中常见眼病的差异,分别有 853 名和 1237 名女性纳入了 NEI VFQ-9 和 NEI VFQ-8 分析。
NEI VFQ-9 量表的 Cronbach α 系数为 0.83,NEI VFQ-8 的 Cronbach α 系数为 0.84。使用这两个问卷,VA 差于 20/40 的女性的综合评分低于 VA 为 20/40 或更好的女性(P<0.001)。轻度、中度和重度双眼 VF 丧失的参与者的综合评分低于无双眼 VF 丧失的参与者(P<0.001)。与双眼均无慢性眼病的女性相比,至少一眼患有至少一种慢性眼病的女性的综合评分较低。
两个问卷在项目间均显示出较高的可靠性,并且与眼病的临床指标具有有效性。未来的研究应该比较这些缩短的调查与 NEI VFQ-25 的特性。