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[塞内加尔达喀尔法恩医院传染病诊所的成人脑型疟疾]

[Cerebral malaria in adults at the Infectious Diseases Clinic in the Fann Hospital in Dakar, Senegal].

作者信息

Soumaré M, Seydi M, Diop S A, Diop B M, Sow P S

机构信息

Université Cheikh-Anta-Diop, Clinique des maladies infectieuses, CHU de Fann, BP 5035 Dakar, Sénégal.

出版信息

Bull Soc Pathol Exot. 2008 Feb;101(1):20-1.

Abstract

This study aimed at describing cerebral malaria cases findings in the Fann Hospital in Dakar. Data were collected from patients files recorded from 2001 to 2005. One hundred and twenty nine cases of cerebral malaria were admitted to the clinic, accounting for 21.4% of all malaria cases. The sex-ratio M/F was 2.48 and the mean age of patients 28.24 years old +/- 13.7 [12-85 years old]. Patients presented with either coma (91.4%) or mental confusion (10.07%) along with fever (80.6%), convulsions (33.3%). Other severe malaria conditions were observed: jaundice (7 cases), severe anaemia (5 cases), acute renal failure (3 cases), and circulatory collapse (3 cases). Acute pulmonary infection (4 cases) and Salmonella bacteraemia (2 cases) occurred as complications during patient's hospitalisation. The case fatality rate was 20.2% (26 deaths). No neurological sequelae were found among survivors. Cerebral malaria lethality is still high enough to urge for the improvement of working conditions in our clinic. Together with promotion of preventive measures in the community better health care services will help to reduce malaria related morbidity and mortality.

摘要

本研究旨在描述达喀尔法恩医院的脑型疟病例的发现情况。数据收集自2001年至2005年记录的患者档案。129例脑型疟患者入住该诊所,占所有疟疾病例的21.4%。男女比例为2.48,患者平均年龄为28.24岁±13.7岁[12 - 85岁]。患者表现为昏迷(91.4%)或精神错乱(10.07%),伴有发热(80.6%)、抽搐(33.3%)。还观察到其他严重疟疾情况:黄疸(7例)、严重贫血(5例)、急性肾衰竭(3例)和循环衰竭(3例)。急性肺部感染(4例)和沙门菌败血症(2例)在患者住院期间作为并发症发生。病死率为20.2%(26例死亡)。幸存者中未发现神经后遗症。脑型疟的致死率仍然足够高,促使我们改善诊所的工作条件。与在社区推广预防措施一起,更好的医疗服务将有助于降低疟疾相关的发病率和死亡率。

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