Jerant Anthony, Kravitz Richard, Moore-Hill Monique, Franks Peter
Department of Family and Community Medicine, University of California Davis School of Medicine (UCDSOM), 4860 Y Street, Suite 2300, Sacramento, CA 95817, USA.
Med Care. 2008 May;46(5):523-31. doi: 10.1097/MLR.0b013e31815f53a4.
Identifying moderators of the effects of self-efficacy enhancing interventions could facilitate their refinement and more targeted, cost-effective delivery. Current theories and data concerning the potential moderating effect of depressive symptoms on interventions to enhance patient chronic illness self-management self-efficacy are conflicting.
To explore the moderating effect of depressive symptoms on the effect of an intervention to enhance patient self-efficacy for self-managing chronic illness.
Regression analyses using baseline and postintervention (6 weeks) data from an ongoing randomized controlled trial.
Patients (N = 415) aged >or=40 years recruited from a primary care network in Northern California with arthritis, asthma, chronic obstructive pulmonary disease, congestive heart failure, depression, and/or diabetes mellitus, plus impairment in >or=1 basic activity, and/or a score of >or=4 on the 10-item Center for Epidemiologic Studies Depression Scale (CES-D).
Stanford self-efficacy scale, self-reported depression, CES-D, and Medical Outcomes Study Short Form health status questionnaire (SF-36) Mental Component Summary score.
Regression analyses revealed the intervention was effective primarily in those with self-reported depression (interaction effect F = 8.24, P = 0.0003), highest CES-D score category (F = 5.68, P = 0.0037), and lowest (most depressed) Mental Component Summary-36 tercile (F = 4.36, P = 0.0135).
Individuals with more depressive symptoms seem more likely to experience self-efficacy gains from chronic illness self-management training than individuals with less depressive symptoms. Future self-management training studies should stratify subjects within study groups by depressive symptom level to further explore its potential moderating effect.
确定自我效能增强干预效果的调节因素有助于改进这些干预措施,并实现更具针对性、更具成本效益的实施。目前有关抑郁症状对增强患者慢性病自我管理自我效能干预措施潜在调节作用的理论和数据相互矛盾。
探讨抑郁症状对增强患者慢性病自我管理自我效能干预效果的调节作用。
使用一项正在进行的随机对照试验的基线和干预后(6周)数据进行回归分析。
从北加利福尼亚州初级保健网络招募的年龄≥40岁的患者(N = 415),患有关节炎、哮喘、慢性阻塞性肺疾病、充血性心力衰竭、抑郁症和/或糖尿病,且至少一项基本活动受损,和/或在10项流行病学研究中心抑郁量表(CES-D)上得分≥4分。
斯坦福自我效能量表、自我报告的抑郁、CES-D以及医学结局研究简表健康状况问卷(SF-36)心理成分汇总得分。
回归分析显示,该干预主要对那些自我报告有抑郁症状的患者有效(交互效应F = 8.24,P = 0.0003)、CES-D得分最高类别(F = 5.68,P = 0.0037)以及心理成分汇总-36得分最低(抑郁程度最高)三分位数的患者有效(F = 4.36,P = 0.0135)。
与抑郁症状较轻的个体相比,抑郁症状较多的个体似乎更有可能从慢性病自我管理培训中获得自我效能的提升。未来的自我管理培训研究应按抑郁症状水平对研究组内的受试者进行分层,以进一步探讨其潜在的调节作用。