Vianna L G, Macedo V, Costa J M
Núcleo de Medicina Tropical e Nutriçao, Universidad de Brasilia, Brasil.
Rev Inst Med Trop Sao Paulo. 1991 Mar-Apr;33(2):129-36.
The aims of the present study were to measure the frequency of cutaneous, muscular and visceral forms of cysticercosis in anatomopathological examinations and necropsies in the Federal District and to study the clinical aspects of this disease. In 64.911 protocols of anatomopathological examinations reviewed, 30 (0.05%) had the diagnosis of cysticercosis, 90% had cysticerci in the subcutaneous tissue, skeletal muscle or mucous membrane, 3.3% in lymph node and 6.7% in the central nervous system. Two (7.4%) patients had cysticerci in the tongue. In 1520 autopsies protocols reviewed, 25 (1.6%) autopsies with cysticercosis were found. 96% had cysticerci in the central nervous system, 8% in the heart, 8% in the skeletal muscle and 4% in the liver, either isolated or associated with cysticerci in other viscera. 1122 people were also examined. Indirect immunofluorescence and ELISA were the serological tests used in all patients for the diagnosis of cysticercosis. The radiological investigation of the skull and soft tissues was also performed. 59 (5.3%) patients had both serological tests positive (10 had also biopsies with the diagnosis of cysticercosis). The muscular form was found in 42.4%, subcutaneous cysts were present in 20.3% and the visceral form was found in 3.4% of cases. In patients with visceral cysticercosis, the cysts were localized in the heart, pleura, kidney and ovary. Calcifications in the skull and/or soft tissues were demonstrated radiologically in 32 (2.8%) patients with negative serological tests for cysticercosis. The present study suggests a high frequency of subcutaneous and muscular forms of cysticercosis in the Federal District. The visceral form of the disease is also found in various organs, without clinical manifestations of importance.
本研究的目的是测量在联邦区的解剖病理学检查和尸检中囊尾蚴病皮肤、肌肉和内脏型的发生率,并研究该疾病的临床特征。在审查的64911份解剖病理学检查记录中,30例(0.05%)诊断为囊尾蚴病,90%的囊尾蚴位于皮下组织、骨骼肌或黏膜,3.3%位于淋巴结,6.7%位于中枢神经系统。两名(7.4%)患者的舌部有囊尾蚴。在审查的1520份尸检记录中,发现25例(1.6%)尸检有囊尾蚴病。96%的囊尾蚴位于中枢神经系统,8%位于心脏,8%位于骨骼肌,4%位于肝脏,可单独存在或与其他内脏的囊尾蚴合并存在。还对1122人进行了检查。所有患者均采用间接免疫荧光法和酶联免疫吸附测定法进行囊尾蚴病的血清学诊断。还对头骨和软组织进行了放射学检查。59例(5.3%)患者血清学检查均为阳性(其中10例经活检诊断为囊尾蚴病)。肌肉型占42.4%,皮下囊肿占20.3%,内脏型占3.4%。在内脏囊尾蚴病患者中,囊肿位于心脏、胸膜、肾脏和卵巢。32例(2.8%)囊尾蚴病血清学检查阴性的患者经放射学检查显示头骨和/或软组织有钙化。本研究表明,联邦区囊尾蚴病的皮下和肌肉型发生率较高。该疾病的内脏型也见于多个器官,但无重要的临床表现。