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旨在降低脊髓脊膜膨出患者的分流置管率。

Toward reducing shunt placement rates in patients with myelomeningocele.

作者信息

Chakraborty Aabir, Crimmins Darach, Hayward Richard, Thompson Dominic

机构信息

Department of Neurosurgery, Great Ormond Street Hospital for Sick Children, London, United Kingdom.

出版信息

J Neurosurg Pediatr. 2008 May;1(5):361-5. doi: 10.3171/PED/2008/1/5/361.

Abstract

OBJECT

The prevalence of shunt-dependent hydrocephalus in patients with myelomeningocele has been reported to be in the region of 85%, and shunt-related complications are a significant cause of morbidity and mortality in these patients. Since 1997 the authors have adopted a stringent policy with respect to shunt placement in patients with myelomeningocele, reserving this treatment for those with symptomatic hydrocephalus, severe ventricular dilation at the time of presentation, and/or unequivocal progressive ventriculomegaly after primary closure. They report their experience.

METHODS

The authors reviewed all cases of myelomeningocele involving patients who presented to their institution over a 10-year period. They excluded cases in which the primary closure was carried out at another institution or in which there was not at least 12 months of clinical and imaging follow-up. Data regarding shunt insertion shunt-related complications, and clinical outcome were obtained from a review of the clinical records and analyzed.

RESULTS

Fifty-four cases satisfied the inclusion criteria for this study. Shunt insertion was performed in 28 of these cases (51.9%).

CONCLUSIONS

Applying more stringent guidelines for shunt placement, permitting moderate ventricular dilation, and accepting some mild increase in ventricular size after myelomeningocele closure has resulted in a reduced rate of shunt placement compared with previous series. The rate is comparable to that reported following in utero closure of myelomeningocele.

摘要

目的

据报道,脊髓脊膜膨出患者中依赖分流的脑积水患病率约为85%,分流相关并发症是这些患者发病和死亡的重要原因。自1997年以来,作者对脊髓脊膜膨出患者的分流置入采取了严格政策,仅将这种治疗用于有症状性脑积水、就诊时脑室严重扩张和/或初次闭合后明确的进行性脑室扩大的患者。他们报告了自己的经验。

方法

作者回顾了10年间在其机构就诊的所有脊髓脊膜膨出病例。他们排除了在其他机构进行初次闭合的病例或临床和影像学随访时间不足12个月的病例。通过查阅临床记录获得有关分流置入、分流相关并发症和临床结果的数据并进行分析。

结果

54例符合本研究的纳入标准。其中28例(51.9%)进行了分流置入。

结论

与先前的系列研究相比,对分流置入应用更严格的指导原则,允许适度的脑室扩张,并接受脊髓脊膜膨出闭合后脑室大小的一些轻度增加,导致分流置入率降低。该比率与脊髓脊膜膨出宫内闭合后报道的比率相当。

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