• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

旨在降低脊髓脊膜膨出患者的分流置管率。

Toward reducing shunt placement rates in patients with myelomeningocele.

作者信息

Chakraborty Aabir, Crimmins Darach, Hayward Richard, Thompson Dominic

机构信息

Department of Neurosurgery, Great Ormond Street Hospital for Sick Children, London, United Kingdom.

出版信息

J Neurosurg Pediatr. 2008 May;1(5):361-5. doi: 10.3171/PED/2008/1/5/361.

DOI:10.3171/PED/2008/1/5/361
PMID:18447669
Abstract

OBJECT

The prevalence of shunt-dependent hydrocephalus in patients with myelomeningocele has been reported to be in the region of 85%, and shunt-related complications are a significant cause of morbidity and mortality in these patients. Since 1997 the authors have adopted a stringent policy with respect to shunt placement in patients with myelomeningocele, reserving this treatment for those with symptomatic hydrocephalus, severe ventricular dilation at the time of presentation, and/or unequivocal progressive ventriculomegaly after primary closure. They report their experience.

METHODS

The authors reviewed all cases of myelomeningocele involving patients who presented to their institution over a 10-year period. They excluded cases in which the primary closure was carried out at another institution or in which there was not at least 12 months of clinical and imaging follow-up. Data regarding shunt insertion shunt-related complications, and clinical outcome were obtained from a review of the clinical records and analyzed.

RESULTS

Fifty-four cases satisfied the inclusion criteria for this study. Shunt insertion was performed in 28 of these cases (51.9%).

CONCLUSIONS

Applying more stringent guidelines for shunt placement, permitting moderate ventricular dilation, and accepting some mild increase in ventricular size after myelomeningocele closure has resulted in a reduced rate of shunt placement compared with previous series. The rate is comparable to that reported following in utero closure of myelomeningocele.

摘要

目的

据报道,脊髓脊膜膨出患者中依赖分流的脑积水患病率约为85%,分流相关并发症是这些患者发病和死亡的重要原因。自1997年以来,作者对脊髓脊膜膨出患者的分流置入采取了严格政策,仅将这种治疗用于有症状性脑积水、就诊时脑室严重扩张和/或初次闭合后明确的进行性脑室扩大的患者。他们报告了自己的经验。

方法

作者回顾了10年间在其机构就诊的所有脊髓脊膜膨出病例。他们排除了在其他机构进行初次闭合的病例或临床和影像学随访时间不足12个月的病例。通过查阅临床记录获得有关分流置入、分流相关并发症和临床结果的数据并进行分析。

结果

54例符合本研究的纳入标准。其中28例(51.9%)进行了分流置入。

结论

与先前的系列研究相比,对分流置入应用更严格的指导原则,允许适度的脑室扩张,并接受脊髓脊膜膨出闭合后脑室大小的一些轻度增加,导致分流置入率降低。该比率与脊髓脊膜膨出宫内闭合后报道的比率相当。

相似文献

1
Toward reducing shunt placement rates in patients with myelomeningocele.旨在降低脊髓脊膜膨出患者的分流置管率。
J Neurosurg Pediatr. 2008 May;1(5):361-5. doi: 10.3171/PED/2008/1/5/361.
2
[Long-term results of hydrocephalus with myelomeningocele].[脊髓脊膜膨出合并脑积水的长期结果]
No To Shinkei. 1990 Sep;42(9):879-88.
3
Shunt complications in children with myelomeningocele: effect of timing of shunt placement. Clinical article.脊髓脊膜膨出患儿的分流并发症:分流放置时机的影响。临床文章。
J Neurosurg Pediatr. 2009 Jun;3(6):516-20. doi: 10.3171/2009.2.PEDS08476.
4
Postoperative cerebrospinal fluid wound leakage as a predictor of shunt infection: a prospective analysis of 205 cases. Clinical article.术后脑脊液伤口漏作为分流感染的预测指标:205例前瞻性分析。临床文章。
J Neurosurg Pediatr. 2009 Aug;4(2):166-9. doi: 10.3171/2009.3.PEDS08458.
5
Rate of shunt revision as a function of age in patients with shunted hydrocephalus due to myelomeningocele.脊髓脊膜膨出所致分流性脑积水患者中,分流翻修率与年龄的关系。
Neurosurg Focus. 2016 Nov;41(5):E6. doi: 10.3171/2016.8.FOCUS16257.
6
A multicenter prospective cohort study of the Strata valve for the management of hydrocephalus in pediatric patients.一项关于Strata瓣膜治疗小儿脑积水的多中心前瞻性队列研究。
J Neurosurg. 2005 Mar;102(2 Suppl):141-5. doi: 10.3171/jns.2005.102.2.0141.
7
Postnatal ascent of the cerebellar tonsils in Chiari malformation Type II following surgical repair of myelomeningocele.脊髓脊膜膨出手术修复后 Chiari Ⅱ型畸形中小脑扁桃体的产后上升。
J Neurosurg Pediatr. 2008 Sep;2(3):188-93. doi: 10.3171/PED/2008/2/9/188.
8
Prenatal surgery for myelomeningocele and the need for cerebrospinal fluid shunt placement.脊髓脊膜膨出的产前手术及脑脊液分流置管需求
J Neurosurg Pediatr. 2015 Dec;16(6):613-20. doi: 10.3171/2015.7.PEDS15336. Epub 2015 Sep 15.
9
CSF shunt removal in children with hydrocephalus.脑积水患儿脑脊液分流管移除术
Acta Neurochir (Wien). 2005 May;147(5):503-7; discussion 507. doi: 10.1007/s00701-005-0494-6. Epub 2005 Mar 14.
10
Shunt infection and malfunction in patients with myelomeningocele.脊膜脊髓膨出患者的分流感染和故障。
J Neurosurg Pediatr. 2021 Feb 26;27(5):518-524. doi: 10.3171/2020.9.PEDS20313. Print 2021 May 1.

引用本文的文献

1
Differences in brain development and need for CSF diversion based on MMC level: Comparison between prenatal and postnatal repair.基于脊髓脊膜膨出程度的脑发育差异及脑脊液分流需求:产前与产后修复的比较
Childs Nerv Syst. 2025 Jun 11;41(1):209. doi: 10.1007/s00381-025-06851-z.
2
Asymptomatic ventriculomegaly in myelomeningocele: a matched cohort study of neuropsychological outcomes across institutions with varying shunt rates.脊髓脊膜膨出中的无症状脑室扩大:一项对不同分流率机构间神经心理学结果的匹配队列研究。
Childs Nerv Syst. 2025 May 30;41(1):196. doi: 10.1007/s00381-025-06847-9.
3
Adult-onset medulloblastoma presenting in the setting of untreated spina bifida: illustrative case.
成人期髓母细胞瘤在未治疗的脊柱裂背景下出现:病例说明
J Neurosurg Case Lessons. 2025 Mar 31;9(13). doi: 10.3171/CASE24897.
4
Concurrent myelomeningocele and sagittal craniosynostosis: illustrative case.脊髓脊膜膨出与矢状缝早闭并存:病例展示
J Neurosurg Case Lessons. 2025 Jan 6;9(1). doi: 10.3171/CASE24616.
5
Research priorities for improving cognitive and neuropsychological outcomes in hydrocephalus.改善脑积水患者认知和神经心理预后的研究重点
Fluids Barriers CNS. 2024 Dec 31;21(1):109. doi: 10.1186/s12987-024-00602-z.
6
Myelomeningocele: Long-Term Neurosurgical Management.脊髓脊膜膨出:长期神经外科治疗管理。
Adv Tech Stand Neurosurg. 2024;49:95-122. doi: 10.1007/978-3-031-42398-7_6.
7
Reflections upon the intrauterine repair of myelomeningocele.对脊髓脊膜膨出的宫内修复的思考。
Childs Nerv Syst. 2024 May;40(5):1571-1575. doi: 10.1007/s00381-024-06365-0. Epub 2024 Mar 22.
8
Fetal Surgery for Myelomeningocele: Neurosurgical Perspectives.脊髓脊膜膨出的胎儿手术:神经外科视角
Adv Tech Stand Neurosurg. 2023;47:25-48. doi: 10.1007/978-3-031-34981-2_2.
9
Quality of life in children operated for spina bifida; low- and middle-income country perspective.脊柱裂手术患儿的生活质量;低收入和中等收入国家视角
Childs Nerv Syst. 2023 Nov;39(11):3155-3161. doi: 10.1007/s00381-023-05993-2. Epub 2023 May 18.
10
Multidisciplinary spina bifida clinic: the Chicago experience.多学科脊柱裂诊所:芝加哥的经验。
Childs Nerv Syst. 2022 Sep;38(9):1675-1681. doi: 10.1007/s00381-022-05594-5. Epub 2022 Jul 23.