Semple Patrick L, Jane John A, Lopes M Beatriz S, Laws Edward R
Department of Neurosurgery, University of Cape Town, South Africa.
J Neurosurg. 2008 May;108(5):909-15. doi: 10.3171/JNS/2008/108/5/0909.
The aim of this study was to correlate the magnetic resonance (MR) imaging findings in pituitary apoplexy with histopathological results and determine whether the histopathology influences clinical presentation and outcome.
The records of 36 patients with histologically confirmed pituitary apoplexy, who were treated surgically at the University of Virginia Health System between 1996 and 2006, were retrospectively reviewed. The MR images were divided into 3 groups: 1) infarction alone; 2) hemorrhage with or without infarction; and 3) tumor only with no evidence of apoplexy. The histological examination was divided into infarction alone or hemorrhagic infarction/hemorrhage. The MR imaging findings were then correlated with the histopathological results to assess how accurately the histopathology was predicted by the MR imaging. The clinical features and outcomes of the two histopathological groups were also compared.
The MR imaging findings were able to predict the histopathology accurately in the majority of cases. The group of patients with infarction had less severe clinical features and a better outcome than those with hemorrhagic infarction/hemorrhage.
Magnetic resonance imaging findings in the setting of pituitary apoplexy accurately predict the nature of the apoplectic process and help to guide the type and timing of therapy.
本研究旨在将垂体卒中的磁共振（MR）成像结果与组织病理学结果相关联，并确定组织病理学是否会影响临床表现和预后。
回顾性分析1996年至2006年间在弗吉尼亚大学健康系统接受手术治疗的36例经组织学证实为垂体卒中患者的病历。MR图像分为3组：1）单纯梗死；2）伴有或不伴有梗死的出血；3）仅有肿瘤而无卒中证据。组织学检查分为单纯梗死或出血性梗死/出血。然后将MR成像结果与组织病理学结果相关联，以评估MR成像对组织病理学的预测准确性。还比较了两个组织病理学组的临床特征和预后。
在大多数情况下，MR成像结果能够准确预测组织病理学。梗死组患者的临床特征较轻，预后优于出血性梗死/出血组。
垂体卒中情况下的磁共振成像结果能够准确预测卒中过程的性质，并有助于指导治疗类型和时机。
