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Multiple pathways inhibit NHEJ at telomeres.
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Rap1 prevents telomere fusions by nonhomologous end joining.
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3
Structural and functional studies of the Rap1 C-terminus reveal novel separation-of-function mutants.
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Rif2 protects Rap1-depleted telomeres from MRX-mediated degradation in .
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Ku Binding on Telomeres Occurs at Sites Distal from the Physical Chromosome Ends.
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Telomerase, the recombination machinery and Rap1 play redundant roles in yeast telomere protection.
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Rap1 in Candida albicans: an unusual structural organization and a critical function in suppressing telomere recombination.
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Smc5/6 Is a Telomere-Associated Complex that Regulates Sir4 Binding and TPE.
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Mismatch tolerance by DNA polymerase Pol4 in the course of nonhomologous end joining in Saccharomyces cerevisiae.
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Rif1 and Rif2 shape telomere function and architecture through multivalent Rap1 interactions.
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Restriction of Ku translocation protects telomere ends.
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Unwrap RAP1's Mystery at Kinetoplastid Telomeres.
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Rap1 prevents fusions between long telomeres in fission yeast.
EMBO J. 2022 Oct 17;41(20):e110458. doi: 10.15252/embj.2021110458. Epub 2022 Sep 5.
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Rif2 protects Rap1-depleted telomeres from MRX-mediated degradation in .
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Sir3 heterochromatin protein promotes non-homologous end joining by direct inhibition of Sae2.
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本文引用的文献

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The origin recognition complex localizes to telomere repeats and prevents telomere-circle formation.
Curr Biol. 2007 Nov 20;17(22):1989-95. doi: 10.1016/j.cub.2007.10.054.
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MRX-dependent DNA damage response to short telomeres.
Mol Biol Cell. 2007 Aug;18(8):3047-58. doi: 10.1091/mbc.e07-03-0285. Epub 2007 May 30.
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A RAP1/TRF2 complex inhibits nonhomologous end-joining at human telomeric DNA ends.
Mol Cell. 2007 May 11;26(3):323-34. doi: 10.1016/j.molcel.2007.03.023.
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Independent sorting-out of thousands of duplicated gene pairs in two yeast species descended from a whole-genome duplication.
Proc Natl Acad Sci U S A. 2007 May 15;104(20):8397-402. doi: 10.1073/pnas.0608218104. Epub 2007 May 9.
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Distinct faces of the Ku heterodimer mediate DNA repair and telomeric functions.
Nat Struct Mol Biol. 2007 Apr;14(4):301-7. doi: 10.1038/nsmb1214. Epub 2007 Mar 11.
8
A topological mechanism for TRF2-enhanced strand invasion.
Nat Struct Mol Biol. 2007 Feb;14(2):147-54. doi: 10.1038/nsmb1192. Epub 2007 Jan 14.
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Telomere structure and function in trypanosomes: a proposal.
Nat Rev Microbiol. 2007 Jan;5(1):70-5. doi: 10.1038/nrmicro1577. Epub 2006 Dec 11.
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Ku70 stimulates fusion of dysfunctional telomeres yet protects chromosome ends from homologous recombination.
Nat Cell Biol. 2006 Aug;8(8):885-90. doi: 10.1038/ncb1444. Epub 2006 Jul 16.

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