Marzouka E
Laboratorio de Referencia de Hematología, Instituto de Salud Pública, Santiago de Chile.
Rev Med Chil. 1991 Oct;119(10):1160-4.
There are many patients on oral anticoagulant therapy monitored with prothrombin time (Quick Test). Differences in sensitivity of the various types of tissue thromboplastins are the cause of the different results and common therapeutic ranges, calibrated reference thromboplastins with a defined International Sensibility Index (ISI) have become available. The ISI is used to estimate the International Normalized Rate (INR) which is used as a universal scale for the expression of the prothrombin time results in the control of oral anticoagulant therapy.
有许多接受口服抗凝治疗的患者通过凝血酶原时间（Quick Test）进行监测。各种类型的组织凝血活酶敏感性不同，这是导致结果和常用治疗范围存在差异的原因，现已可获得具有明确国际敏感指数（ISI）的校准参考凝血活酶。ISI用于估算国际标准化比值（INR），INR用作在口服抗凝治疗控制中表达凝血酶原时间结果的通用尺度。
