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[睾丸切除后胃固有腺壁外分泌细胞的形态功能分析]

[A morphofunctional analysis of the parietal exocrinocytes of the gastric glands proper after removal of the testes].

作者信息

Matsiuk Ia R, Taranenko T V

出版信息

Arkh Anat Gistol Embriol. 1991 Nov-Dec;101(11-12):49-53.

PMID:1845498
Abstract

In the experiment performed in 52 white male rats by means of light electron microscopy methods, cytochemistry and biochemistry with a subsequent cytophoto- and morphometric analysis, it has been stated that bilateral removal of the testes does not inhibit essentially the differential process of the parietal exocrinocytes, but facilitates the development of certain dystrophic processes in them. The latter are demonstrated as decrease of secretory membranes balance in the cell, of quantitative density of mitochondria, of crysts area, of matrix vacuolization. Activity of oxidoreductase in Krebs cycle, of pentosophosphate shunt and glycolysis decreases. Most of the changes mentioned are not large, but stable. Despite this, acid-producing function of the parietal exocrinocytes is essentially inhibited.

摘要

在一项利用光电子显微镜方法、细胞化学和生物化学手段,并随后进行细胞照相和形态计量分析,对52只白色雄性大鼠开展的实验中,结果表明双侧睾丸切除并未从本质上抑制壁外分泌细胞的分化过程,反而促进了其中某些营养不良性过程的发展。后者表现为细胞内分泌膜平衡的降低、线粒体定量密度的降低、嵴面积的降低、基质空泡化。三羧酸循环中氧化还原酶、磷酸戊糖途径和糖酵解的活性降低。上述大多数变化虽不大,但较为稳定。尽管如此,壁外分泌细胞的产酸功能基本上受到了抑制。

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