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[维生素A缺乏时胃黏膜固有腺体中主要外分泌细胞的超微结构]

[The ultrastructure of the main exocrinocytes in the glands proper of the gastric mucosa in A avitaminosis].

作者信息

Gulich M P, Gnatovskaia S I

出版信息

Morfologiia. 1993 Jan-Feb;104(1-2):94-101.

PMID:8293137
Abstract

The electron microscopic and morphometrical methods were used to study the ultrastructural organization of main exocrinocytes of the proper glands of the mucous membrane of the stomach of rats under conditions of A-avitaminosis. Deficiency of vitamin A causes dystrophic alterations of main exocrinocytes. The fragmentation, degranulation and considerable dilatation of cisterns of the granular endoplasmic reticulum, destruction of the Golgi complex membranes, disturbance of the membranous organization of secretory vacuoles were observed. A conclusion is made of disturbances of the protein-synthesizing function of main exocrinocytes under conditions of A-avitaminosis.

摘要

运用电子显微镜和形态测量学方法,研究了维生素A缺乏条件下大鼠胃黏膜固有腺体主要外分泌细胞的超微结构组织。维生素A缺乏会导致主要外分泌细胞发生营养不良性改变。观察到粗面内质网池的碎片化、脱颗粒和显著扩张,高尔基体复合体膜的破坏,分泌泡膜性组织的紊乱。得出结论,在维生素A缺乏的情况下,主要外分泌细胞的蛋白质合成功能受到干扰。

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