Suer Evren, Gokce Ilker, Yaman Onder, Anafarta Kadri, Göğüş Orhan
Department of Urology, University of Ankara School of Medicine, Ankara, Turkey.
Urology. 2008 Jul;72(1):90-4. doi: 10.1016/j.urology.2008.03.015. Epub 2008 May 2.
To evaluate, in a retrospective, single-center trial, our open prostatectomy outcomes and complications in the past 12 years to emphasize the feasibility of open prostatectomy for large prostates.
A total of 1193 patients underwent open prostatectomy from 1995 to 2007. We retrospectively analyzed the data from 664 patients who had preoperative, operative, and postoperative data available.
The mean patient age was 67.5 years (range 52-86). The mean preoperative prostate-specific antigen value was 9.6 ng/mL (range 1.65-45.6). The mean prostatic weight was 88.7 g (range 45-324) and was significantly different for the 1995-2001 and 2002-2007 groups (73.6 vs 98.2 g, respectively). Of the 664 patients, 208 (31%) had had an indwelling catheter before surgery. The average International Prostate Symptom Score was 21.7 (range 13-32) preoperatively and 10.6 (range 8-18) postoperatively (P <.005). The average hospitalization was 6.74 days (range 4-14). Blood transfusion was required in 12.7% of the patients either intraoperatively or postoperatively. Postoperatively, 82 patients (12.3%) had urinary tract infections, 22 (3.2%) had bladder neck obstruction, 5 (0.7%) had urinary incontinence, and 15 (2.3%) had a ureteral meatus stricture.
Open prostatectomy is a feasible treatment option for patients with a large prostate and also for patients with additional bladder pathologic findings such as bladder calculi or diverticula for whom endoscopic treatment modalities are not appropriate. Consequently, open prostatectomy is still the primary option for patients with a prostate greater than 100 cm(3) and preserves its importance in urology practice, even in the presence of endoscopic innovations.
在一项回顾性单中心试验中,评估我们在过去12年中开放性前列腺切除术的结果及并发症,以强调开放性前列腺切除术治疗大体积前列腺的可行性。
1995年至2007年共有1193例患者接受了开放性前列腺切除术。我们回顾性分析了664例有术前、术中和术后数据的患者资料。
患者平均年龄为67.5岁(范围52 - 86岁)。术前前列腺特异性抗原平均水平为9.6 ng/mL(范围1.65 - 45.6)。前列腺平均重量为88.7 g(范围45 - 324 g),1995 - 2001年组和2002 - 2007年组有显著差异(分别为73.6 g和98.2 g)。664例患者中,208例(31%)术前留置过导尿管。术前国际前列腺症状评分平均为21.7(范围13 - 32),术后为10.6(范围8 - 18)(P <.005)。平均住院时间为6.74天(范围4 - 14天)。12.7%的患者术中或术后需要输血。术后,82例患者(12.3%)发生尿路感染,22例(3.2%)发生膀胱颈梗阻,5例(0.7%)发生尿失禁,15例(2.3%)发生尿道口狭窄。
开放性前列腺切除术对于大体积前列腺患者以及存在膀胱结石或憩室等膀胱其他病理表现而不适合内镜治疗的患者是一种可行的治疗选择。因此,开放性前列腺切除术仍是前列腺体积大于100 cm³患者的主要选择,即使在内镜技术不断创新的情况下,其在泌尿外科实践中仍具有重要意义。