Chung Alice P, Sacchini Virgilio
Breast Service, Department of Surgery, Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, New York, NY 10065, USA.
Surg Oncol. 2008 Dec;17(4):261-6. doi: 10.1016/j.suronc.2008.03.004. Epub 2008 May 5.
Surgical treatment of breast cancer has evolved from radical mastectomy with routine removal of the nipple-areolar complex (NAC) to breast conservative therapy with preservation of the breast and NAC. When breast conservation is not appropriate or the patient desires mastectomy for risk reduction, conventional therapy still consists of mastectomy with removal of the NAC, followed by reconstruction. Rising interest in improved cosmesis has led to the introduction of the skin-sparing and nipple-sparing mastectomy (NSM) as potential alternatives to mastectomy. There has been much controversy regarding the oncologic safety of these procedures, and the NSM has also introduced a set of complications, such as nipple and areolar necrosis, that are not a concern with total mastectomy. From our review of the literature, we feel that NSM may be a viable option in the appropriate setting, and that its risks and complications are acceptable when compared to the traditional surgical treatment of breast cancer.
乳腺癌的外科治疗已从常规切除乳头乳晕复合体(NAC)的根治性乳房切除术发展为保留乳房和NAC的保乳治疗。当保乳不合适或患者为降低风险而希望进行乳房切除时,传统治疗仍包括切除NAC的乳房切除术,随后进行重建。对改善美容效果的兴趣日益增加,促使引入了保留皮肤和保留乳头的乳房切除术(NSM),作为乳房切除术的潜在替代方法。关于这些手术的肿瘤学安全性存在诸多争议,并且NSM还引入了一系列并发症,如乳头和乳晕坏死,而全乳房切除术则不存在这些问题。通过对文献的回顾,我们认为NSM在适当的情况下可能是一种可行的选择,并且与传统的乳腺癌手术治疗相比,其风险和并发症是可以接受的。