Chepyala Pavan, Olden Kevin W
Department of Gastroenterology and Hepatology, University of Arkansas for Medical Sciences, Little Rock, Arkansas 72205, USA.
Clin Gastroenterol Hepatol. 2008 Jun;6(6):710-2. doi: 10.1016/j.cgh.2008.01.017. Epub 2008 May 5.
Cannabis is commonly recognized for its antiemetic properties. However, chronic cannabis use can lead to paroxysmal vomiting. In some patients this vomiting can take on a pattern identical to cyclic vomiting syndrome. Interestingly cyclic vomiting syndrome has been associated with compulsive bathing which patients report can relieve their intense feelings of nausea and lessen their vomiting intensity. We report a case of a patient with chronic cannabis use who developed symptoms similar to cyclic vomiting syndrome who also engaged in compulsive bathing behavior as observed by members of the medical and nursing staff. The patient reported that frequent hot showers would prevent him from vomiting and also relieve his concomitant abdominal pain. Previous hospitalizations at our hospital for the same complaint also noted similar showering behavior. During the hospital stay, the patient agreed to engage in a outpatient drug rehabilitation program which he subsequently completed. Abstinence from cannabis use caused the patients vomiting symptoms and abdominal pain to disappear completely. Likewise, his compulsive showering behavior also ceased. Other investigators have reported similar findings in patients with cyclic vomiting syndrome who initially used cannabis to treat their vomiting episodes but subsequently found that it contributed to their vomiting. Our patient has lead us to conclude that in patients seen for chronic severe vomiting and abdominal pain which has no obvious structural or chemical etiology and which is accompanied by compulsive showering and/or bathing behavior a diagnosis of cyclic vomiting syndrome with concomitant cannabis abuse needs to be considered.
大麻因其止吐特性而广为人知。然而,长期使用大麻会导致阵发性呕吐。在一些患者中,这种呕吐可能呈现出与周期性呕吐综合征相同的模式。有趣的是,周期性呕吐综合征与强迫性沐浴有关,患者报告称这可以缓解他们强烈的恶心感并减轻呕吐强度。我们报告了一例长期使用大麻的患者,其出现了类似于周期性呕吐综合征的症状,医护人员观察到该患者还存在强迫性沐浴行为。患者报告称,频繁洗热水澡可以防止他呕吐,并缓解其伴随的腹痛。此前该患者因同样的症状在我院住院时也有类似的沐浴行为。住院期间,患者同意参加门诊戒毒康复项目,随后他完成了该项目。戒除大麻使用后,患者的呕吐症状和腹痛完全消失。同样,他的强迫性沐浴行为也停止了。其他研究人员在周期性呕吐综合征患者中也报告了类似的发现,这些患者最初使用大麻来治疗呕吐发作,但后来发现大麻导致了他们的呕吐。我们的患者让我们得出结论,对于因慢性严重呕吐和腹痛前来就诊、无明显结构或化学病因且伴有强迫性淋浴和/或沐浴行为的患者,需要考虑周期性呕吐综合征伴大麻滥用的诊断。