Bodo Michael, Thuróczy György, Pánczél Gyula, Sipos Kornél, Iliás Lajos, Szonyi Péter, Bodó Mike, Nebella Tamás, Bányász Attila, Nagy Zoltán
Chemical Works of Gedeon Richter Ltd, Budapest, Hungary.
Ideggyogy Sz. 2008 Mar 30;61(3-4):87-96.
A multi-faceted survey was conducted in 1992-94 to ascertain the somatic, mental and socio-economic conditions of the residents of a village in eastern Hungary. Here we report data on prevalence of somatic disorders from the survey.
a) To collect and compare prevalence of known cardiovascular disease, including stroke risk factors, in a specific population (a Hungarian village); b) to test a computer-based mass screening device ("Cerberus") designed to identify individuals in the test population at high risk for stroke; c) to compare results obtained with Cerberus with known stroke risk/cardiovascular disease factors and traditional medical records.
A cross-sectional survey (546 subjects) was conducted in Csengersima in the early 1990s, using the Cerberus screening system, which includes: 1. a questionnaire addressing the risk factors for stroke/cardiovascular disease; 2. amplifiers to record the pulse waves of cerebral (rheoencephalography) and peripheral arteries, electrocardiogram and electroencephalogram. Additionally, subjects were measured for carotid stenosis by Doppler ultrasound and 12-lead electrocardiogram; they were also screened for blood cholesterol, glucose, and triglyceride levels.
Prevalence of the following stroke risk factors was identified: overweight, 63.25%; sclerotic brain arteries by rheoencephalogram, 54.29%; heart disease, 37.92%; pathologic carotid flow, 34.24%; smoking, 30.55%; high blood cholesterol, 28.70%; hypertension, 27.83%; high triglyceride, 24.35%; abnormality of electrocardiogram, 20%; high glucose, 15.95%; symptoms of transient ischemic attack, 16.07%; alcohol abuse, 6.74%; and diabetes, 4.53%.
The study demonstrates a possible model for primary cardiovascular disease/stroke prevention. The simple, noninvasive test uses the bioimpedance method of measurement. This method offers a standardizable, cost-effective, practical technique for mass screenings by identifying the population at high risk for cardiovascular disturbances, especially cerebrovascular disease. In this model, the rheoencephalogram can detect cerebrovascular arteriosclerosis in the susceptibility/presymptomatic phase, earlier than the Doppler ultrasound technique. The method also provides a model for storing analog physiological signals in a computer-based medical record and the first steps of turning it into an expert system also tested.
1992 - 1994年进行了一项多方面的调查，以确定匈牙利东部一个村庄居民的身体、心理和社会经济状况。在此，我们报告该调查中躯体疾病的患病率数据。
a）收集并比较特定人群（一个匈牙利村庄）中已知心血管疾病（包括中风危险因素）的患病率；b）测试一种基于计算机的大规模筛查设备（“冥卫一”），旨在识别测试人群中中风高危个体；c）将使用“冥卫一”获得的结果与已知的中风风险/心血管疾病因素及传统病历进行比较。
20世纪90年代初在森盖尔西马进行了一项横断面调查（546名受试者），使用“冥卫一”筛查系统，该系统包括：1. 一份关于中风/心血管疾病危险因素的问卷；2. 用于记录脑动脉（脑电阻抗图）和外周动脉脉搏波、心电图和脑电图的放大器。此外，通过多普勒超声和12导联心电图测量受试者的颈动脉狭窄情况；还对他们进行了血胆固醇、血糖和甘油三酯水平的筛查。
确定了以下中风危险因素的患病率：超重，63.25%；脑电阻抗图显示脑动脉硬化，54.29%；心脏病，37.92%；病理性颈动脉血流，34.24%；吸烟，30.55%；高血胆固醇，28.70%；高血压，27.8%；高甘油三酯，24.35%；心电图异常，20%；高血糖，15.95%；短暂性脑缺血发作症状，16.07%；酗酒，6.74%；糖尿病，4.53%。
该研究展示了一种原发性心血管疾病/中风预防的可能模式。这种简单的非侵入性测试采用生物阻抗测量方法。该方法通过识别心血管紊乱尤其是脑血管疾病的高危人群，为大规模筛查提供了一种可标准化、经济高效且实用的技术。在这个模式中，脑电阻抗图能够在易感性/症状前期检测到脑血管动脉硬化，比多普勒超声技术更早。该方法还为在基于计算机的病历中存储模拟生理信号提供了一个模式，并且将其转化为专家系统的初步步骤也经过了测试。
