Ivliev Alexander E, 't Hoen Peter A C, Villerius Michel P, den Dunnen Johan T, Brandt Bernd W
Center for Human and Clinical Genetics, Leiden University Medical Center, Leiden, The Netherlands.
Nucleic Acids Res. 2008 Jul 1;36(Web Server issue):W327-31. doi: 10.1093/nar/gkn213. Epub 2008 May 7.
The major public microarray repositories Gene Expression Omnibus and ArrayExpress are growing rapidly. This enables meta-analysis studies, in which expression data from multiple individual studies are combined. To facilitate these types of studies, we developed Microarray Retriever for searching and retrieval of data from GEO and ArrayExpress. The tool allows access to the two repositories simultaneously, to search in the repositories using complex queries, to retrieve microarray data for published articles and to download data in one structured archive. The tool is available on the web at: http://www.lgtc.nl/MaRe/
主要的公共微阵列数据库基因表达综合数据库(Gene Expression Omnibus)和ArrayExpress正在迅速增长。这使得元分析研究成为可能,即在元分析研究中,来自多个独立研究的表达数据可以被整合。为了促进这类研究,我们开发了微阵列检索工具(Microarray Retriever),用于从基因表达综合数据库和ArrayExpress中搜索和检索数据。该工具允许同时访问这两个数据库,使用复杂查询在数据库中进行搜索,为已发表的文章检索微阵列数据,并以一个结构化存档的形式下载数据。该工具可通过以下网址在线获取:http://www.lgtc.nl/MaRe/