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骨关节炎的浴疗法。一项Cochrane系统评价

Balneotherapy for osteoarthritis. A cochrane review.

作者信息

Verhagen Arianne, Bierma-Zeinstra Sita, Lambeck Johan, Cardoso Jefferson Rosa, de Bie Rob, Boers Maarten, de Vet Henrica C W

机构信息

Department of General Practice, Erasmus Medical Centre University, Rotterdam, The Netherlands.

出版信息

J Rheumatol. 2008 Jun;35(6):1118-23. Epub 2008 May 1.

Abstract

OBJECTIVE

Balneotherapy (or spa therapy, mineral baths) for patients with arthritis is one of the oldest forms of therapy. We assessed effectiveness of balneotherapy for patients with osteoarthritis (OA).

METHODS

We performed a broad search strategy to retrieve eligible studies, selecting randomized controlled trials comparing balneotherapy with any intervention or with no intervention. Two authors independently assessed quality and extracted data. Disagreements were solved by consensus. In the event of clinical heterogeneity or lack of data we refrained from statistical pooling.

RESULTS

Seven trials (498 patients) were included in this review: one performed an intention-to-treat analysis, 2 provided data for our own analysis, and one reported a "quality of life" outcome. We found silver-level evidence of mineral baths compared to no treatment (effect sizes 0.34-1.82). Adverse events were not measured or found in included trials.

CONCLUSION

We found silver-level evidence concerning the beneficial effects of mineral baths compared to no treatment. Of all other balneological treatments, no clear effects were found. However, the scientific evidence is weak because of the poor methodological quality and the absence of an adequate statistical analysis and data presentation.

摘要

目的

对关节炎患者进行温泉疗法(或水疗、矿泉浴)是最古老的治疗形式之一。我们评估了温泉疗法对骨关节炎(OA)患者的有效性。

方法

我们实施了广泛的检索策略以获取符合条件的研究,选择将温泉疗法与任何干预措施或不进行干预进行比较的随机对照试验。两位作者独立评估质量并提取数据。分歧通过共识解决。如果存在临床异质性或数据不足,我们不进行统计合并。

结果

本综述纳入了7项试验(498例患者):1项进行了意向性分析,2项提供了我们自己分析的数据,1项报告了“生活质量”结果。我们发现与不治疗相比,矿泉浴有中等强度证据(效应量0.34 - 1.82)。纳入试验中未测量或发现不良事件。

结论

我们发现与不治疗相比,矿泉浴有中等强度证据表明其有益效果。对于所有其他水疗治疗,未发现明确效果。然而,由于方法学质量差以及缺乏充分的统计分析和数据呈现,科学证据较弱。

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