Department of Ophthalmology, Stoke Mandeville Hospital, Aylesbury, UK. fcuthbertson@ doctors.org.uk
Eye (Lond). 2009 Apr;23(4):877-83. doi: 10.1038/eye.2008.122. Epub 2008 May 9.
To look for objective and subjective differences between three types of aspheric intraocular lens implants and their spherical counterparts.
Thirty patients were randomised to receive one of six lens implants including three aspheric lenses and their spherical counterparts. Pre and postoperative testing was carried out including visual acuity, contrast sensitivity and wavefront analysis. All patients were asked to fill in a visual function questionnaire (modification of cataract TyPE) to assess subjective differences in visual quality.
There was no significant difference between groups for best-corrected visual acuity. Contrast sensitivity testing showed the Tecnis lens to perform better than the Cee-on Edge in all lighting conditions with significant differences at 3 and/or 6 cycles/degree in three out of four lighting conditions. No significant differences in contrast sensitivity were seen between the other lens pairs. All aspheric lenses showed less spherical aberration than their spherical pairs with statistical significance reached in two out of three pairs (the Ceeon Edge vs Tecnis, and Acrysof Natural vs IQ). The questionnaire revealed no evidence of improved subjective vision with the aspheric lenses compared to the spherical lenses.
This pilot study concurs with previously published trials in showing decreased spherical aberration and improved contrast sensitivity with aspheric lenses compared to spherical lenses. There was no evidence that the patients implanted with aspheric lenses rate their quality of vision higher than those implanted with spherical lenses. Study numbers were small and larger numbers may be required to demonstrate statistical differences in subjective data.
寻找三种非球面人工晶状体与相应球面晶状体之间的客观和主观差异。
将 30 名患者随机分为六组,分别接受三种非球面晶状体及其相应球面晶状体之一的植入。进行术前和术后测试,包括视力、对比敏感度和波前分析。所有患者均需填写视觉功能问卷(白内障 TYPE 改良版),以评估视觉质量的主观差异。
最佳矫正视力在各组间无显著差异。对比敏感度测试显示,在所有照明条件下,Tecnis 晶状体的表现均优于 Cee-on Edge,在四种照明条件中的三种中,差异具有统计学意义,在 3 和/或 6 个周期/度。其他两对晶状体之间的对比敏感度无显著差异。所有非球面晶状体的球差均低于相应的球面晶状体,其中两对具有统计学意义(Ceeon Edge 与 Tecnis,以及 Acrysof Natural 与 IQ)。问卷调查显示,与球面晶状体相比,非球面晶状体并未改善患者的主观视觉。
本初步研究与先前发表的试验一致,表明与球面晶状体相比,非球面晶状体可降低球差,提高对比敏感度。但植入非球面晶状体的患者并未比植入球面晶状体的患者报告更高的视觉质量。研究数量较少,可能需要更大的样本量来证明主观数据的统计学差异。