Sandoval H P, Fernández de Castro L E, Vroman D T, Solomon K D
Magill Research Center for Vision Correction, Storm Eye Institute, Medical University of South Carolina, Charleston, SC 29425, USA.
Eye (Lond). 2008 Dec;22(12):1469-75. doi: 10.1038/sj.eye.6702925. Epub 2007 Jul 6.
To determine vision quality when testing two acrylic intraocular lenses (IOLs), AcrysofIQ and AcrysofSingle-Piece, after routine cataract extraction and IOL implantation.SettingStorm Eye Institute and Magill Research Center for Vision Correction, Medical University of South Carolina, Charleston, SC, USA.
Prospective, randomized, double-masked study that included 53 eyes of 27 patients who underwent bilateral cataract extraction and IOL implantation. Patients were randomly divided into two groups depending on the type of IOL implanted: AcrysofIQ or AcrysofSingle-Piece. Preoperative, 1- and 3-month postoperative evaluations included ETDRS visual acuity, photopic contrast sensitivity, pupil size, wavefront testing, and a subjective questionnaire. Comparisons between the two groups and comparisons to baseline were made at each visit. P<0.05 was considered statistically significant.
Preoperative, statistically significant differences were evident in response to the subjective questionnaire (near activities, driving dimensions, and overall score) between the two groups. Postoperatively there was a greater increase in contrast sensitivity at 1 and 3 months in the AcrysofIQ group when compared to baseline. Patients with AcrysofIQ IOL had a significant reduction in total high-order aberrations (HOA) and spherical aberration (SA) when compared to those patients with AcrysofSingle-Piece at 1 and 3 months and to baseline. Postoperative patient satisfaction showed no difference among the groups.
The use of a new aspheric acrylic IOL may improve the quality of vision as a result of the reduction of total HOA and SA.
在常规白内障摘除及人工晶状体(IOL)植入术后,测试两种丙烯酸酯人工晶状体(AcrysofIQ和Acrysof单片式)时确定视觉质量。地点:美国南卡罗来纳州查尔斯顿市南卡罗来纳医科大学斯托姆眼科研究所和马吉尔视力矫正研究中心。
前瞻性、随机、双盲研究,纳入27例接受双侧白内障摘除及IOL植入的患者的53只眼。根据植入的IOL类型,患者被随机分为两组:AcrysofIQ组或Acrysof单片式组。术前、术后1个月和3个月的评估包括ETDRS视力、明视觉对比敏感度、瞳孔大小、波前测试和一份主观问卷。每次随访时对两组进行比较,并与基线进行比较。P<0.05被认为具有统计学意义。
术前,两组在主观问卷(近视力活动、驾驶维度和总分)的回答上存在明显的统计学差异。术后,与基线相比,AcrysofIQ组在1个月和3个月时对比敏感度有更大的提高。与Acrysof单片式组患者以及基线相比,植入AcrysofIQ IOL的患者在1个月和3个月时总高阶像差(HOA)和球差(SA)显著降低。术后患者满意度在各组之间没有差异。
使用新型非球面丙烯酸酯IOL可能由于总HOA和SA的降低而改善视觉质量。