Loudon P T, Roy P
NERC Institute of Virology and Environmental Microbiology, Oxford, England.
Virology. 1991 Feb;180(2):798-802. doi: 10.1016/0042-6822(91)90094-r.
Bluetongue virus (BTV) VP1 protein, a component of the viral RNA-directed RNA polymerase, but not the VP4 or VP6 proteins, was specifically incorporated into baculovirus expressed BTV core-like particles (composed of VP3 and VP7) and BTV virus-like particles (composed of VP2, VP3, VP5, and VP7). The VP1 protein has been shown to be associated with subcore particles composed of VP3. The data suggest that the VP1 protein of BTV has both enzymatic and structural roles in the virus life cycle.
蓝舌病病毒（BTV）的VP1蛋白是病毒RNA依赖性RNA聚合酶的一个组成部分，而非VP4或VP6蛋白，它被特异性地整合到杆状病毒表达的BTV核心样颗粒（由VP3和VP7组成）和BTV病毒样颗粒（由VP2、VP3、VP5和VP7组成）中。VP1蛋白已被证明与由VP3组成的亚核心颗粒相关。这些数据表明，BTV的VP1蛋白在病毒生命周期中兼具酶促和结构作用。
