Yin Meng, Rouvière Olivier, Glaser Kevin J, Ehman Richard L
Department of Radiology, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA.
Magn Reson Imaging. 2008 Jul;26(6):770-80. doi: 10.1016/j.mri.2008.01.019. Epub 2008 May 7.
Magnetic resonance elastography (MRE) is a technique for quantifying the acoustic response of biological tissues to propagating waves applied at low frequencies in order to evaluate mechanical properties. Application-specific MRE drivers are typically required to effectively deliver shear waves within the tissue of interest. Surface MRE drivers with transversely oriented vibrations have often been used to directly generate shear waves. These drivers may have disadvantages in certain applications, such as poor penetration depth and inflexible orientation. Therefore, surface MRE drivers with longitudinally oriented vibrations are used in some situations. The purpose of this work was to investigate and optimize a longitudinal driver system for MRE applications. A cone-like hemispherical distribution of shear waves being generated by these drivers and the wave propagation being governed by diffraction in the near field are shown. Using MRE visualization of the vector displacement field, we studied the properties of the shear wave field created by longitudinal MRE drivers of various sizes to identify optimum shear wave imaging planes. The results offer insights and improvements in both experimental design and imaging plane selection for 2-D MRE data acquisition.
磁共振弹性成像(MRE)是一种用于量化生物组织对低频传播波的声学响应以评估其力学特性的技术。通常需要特定应用的MRE驱动装置才能在感兴趣的组织内有效地传递剪切波。具有横向振动的表面MRE驱动装置常常被用于直接产生剪切波。这些驱动装置在某些应用中可能存在缺点,如穿透深度不佳和方向不灵活。因此,在某些情况下会使用具有纵向振动的表面MRE驱动装置。这项工作的目的是研究和优化用于MRE应用的纵向驱动系统。展示了由这些驱动装置产生的呈锥状半球形分布的剪切波以及在近场中由衍射控制的波传播。利用MRE对矢量位移场的可视化,我们研究了各种尺寸的纵向MRE驱动装置所产生的剪切波场的特性,以确定最佳剪切波成像平面。研究结果为二维MRE数据采集的实验设计和成像平面选择提供了见解和改进。