Eye Center, School of Medicine, Affiliated Second Hospital, Zhejiang University, Hangzhou, P.R. China.
J Glaucoma. 2014 Feb;23(2):119-24. doi: 10.1097/IJG.0b013e318268518d.
To evaluate the safety and efficacy of microcoaxial phacoemulsification combined with viscogoniosynechialysis in managing refractory acute angle-closure glaucoma (AACG) unresponsive to conventional therapy.
Seventeen consecutive eyes of patients with AACG>270 degrees peripheral anterior synechiae were treated with microcoaxial phacoemulsification combined with viscogoniosynechialysis. After intraocular lens implantation, a heavy viscoelastic agent was used to deepen the anterior chamber, and then injected near the angle for 360 degrees without touching any ocular structure, to release the peripheral anterior synechiae under gonioscopy. The viscoelastic agent was then removed.
Intraocular pressure was reduced from a median of 45.0 mm Hg initially to 15.0 mm Hg after the combined procedures at the final follow-up visit (P<0.001). All angles showed exposure of the trabecular meshwork over 360 degrees postoperatively without residual synechiae. The mean best corrected visual acuity improved from 0.7 to 0.18 logMAR at 6-month follow-up (P<0.001). Surgically induced astigmatism was 0.29 at 6-month follow-up. There was a 6.4% reduction in the mean corneal endothelial cell count. No severe complications were observed in any patient.
Microcoaxial phacoemulsification combined with viscogoniosynechialysis is an effective and safe treatment for managing refractory AACG. Using a 2.2-mm incision caused less surgically induced astigmatism and also improved visual quality.
评估微同轴超声乳化联合黏弹剂松解房角粘连术治疗常规治疗无效的难治性急性闭角型青光眼(AACG)的安全性和有效性。
对 17 例 AACG>270 度周边前房粘连患者行微同轴超声乳化联合黏弹剂松解房角粘连术。人工晶状体植入后,使用重比重黏弹剂加深前房,然后在房角 360 度无接触任何眼结构的情况下注射,在房角镜下松解周边前房粘连。然后去除黏弹剂。
眼压从最初的中位数 45.0mmHg 降低至联合手术后的终末随访时的 15.0mmHg(P<0.001)。所有角度术后均显示小梁网暴露超过 360 度,无残留粘连。最佳矫正视力从术前的 0.7 提高至术后 6 个月的 0.18 logMAR(P<0.001)。术后 6 个月平均散光为 0.29。平均角膜内皮细胞计数减少 6.4%。无严重并发症发生。
微同轴超声乳化联合黏弹剂松解房角粘连术是治疗难治性 AACG 的有效且安全的方法。使用 2.2mm 的切口引起的散光较小,也提高了视觉质量。