Tang Yao-Ji, Chen Ying, Yao Min-Na, Li Yao-Qun
Department of Chemistry and The Key Laboratory of Analytical Sciences of the Ministry of Education, College of Chemistry and Chemical Engineering, Xiamen University, Siming South Road 422, Xiamen 361005, China.
J Pharm Biomed Anal. 2008 Aug 5;47(4-5):978-80. doi: 10.1016/j.jpba.2008.03.029. Epub 2008 Apr 8.
Total internal reflection (TIR) technique is an interface-specific tool and resonance light scattering (RLS) is of high sensitivity. The combination of both approaches is introduced into the solid/liquid interface for the first time. The behaviors of mixture of TPPS and BSA at the interface have been studied with total internal reflection resonance light scattering (TIR-RLS). The preliminary experimental results indicate that TIR-RLS is a good approach to study the interaction and distinguish the states of macromolecules at the solid/liquid interface.
全内反射（TIR）技术是一种特定于界面的工具，而共振光散射（RLS）具有高灵敏度。这两种方法的结合首次被引入到固/液界面。利用全内反射共振光散射（TIR-RLS）研究了TPPS与BSA混合物在该界面的行为。初步实验结果表明，TIR-RLS是研究固/液界面处大分子相互作用和区分其状态的一种良好方法。
