Aral Ali, Yalçin Serdar, Karabuda Zihni Cuneyt, Anil Ata, Jansen John A, Mutlu Zihni
Department of Oral Implantology, Faculty of Dentistry, Istanbul University, Turkey.
Clin Oral Implants Res. 2008 Jun;19(6):612-7. doi: 10.1111/j.1600-0501.2007.01518.x.
The aim of the present study was to evaluate the efficiency of injectable CaP cement as a graft material around dental implants in the maxillary sinus augmentation procedure.
Bilateral sinus augmentation process was carried out in three sheep and two implants were inserted during the same session. Out of a total of 12 installed implants, eight belonged to the so-called experimental group. In the experimental group, injectable CaP cement was used as augmentation material while autologous bone served as control.
Histological examination revealed that newly formed bone surrounded the cement completely without an intervening fibrous tissue layer. Following a healing period of 12 weeks, mean bone-to-implant contact (BIC) values in the experimental and control groups were 36+/-5 and 37+/-3, respectively. The percentage of BIC was comparable with other experimental sinus augmentation studies. Further, it appeared that the thickness of the cortical bone that covered the outer surface of the maxillary sinus was < 2-3 mm, which affected the primary stability of the implants negatively.
CaP cement is indeed effective to stimulate bone formation in the sinus elevation procedure. Nevertheless, additional improvements in the cement composition are required to allow final clinical utilization of the material.
本研究旨在评估可注射磷酸钙骨水泥作为上颌窦提升术中牙种植体周围植骨材料的有效性。
对三只绵羊进行双侧窦提升术，并在同一阶段植入两颗种植体。在总共植入的12颗种植体中，8颗属于所谓的实验组。在实验组中，使用可注射磷酸钙骨水泥作为植骨材料，自体骨作为对照。
组织学检查显示，新形成的骨完全包裹了骨水泥，中间没有纤维组织层。经过12周的愈合期后，实验组和对照组的平均骨与种植体接触（BIC）值分别为36±5和37±3。BIC的百分比与其他实验性窦提升研究相当。此外，覆盖上颌窦外表面的皮质骨厚度似乎<2 - 3毫米，这对种植体的初始稳定性产生了负面影响。
磷酸钙骨水泥在窦提升术中确实能有效刺激骨形成。然而，需要对骨水泥成分进行进一步改进，以便该材料最终能用于临床。
