Asato Yutaka, Taira Kiyohito, Yamamoto Yu-Ichi, Uezato Hiroshi
Division of Dermatology, Department of Medicine, University of the Ryukyu, 207 Uehara, Nishiara town, Okinawa, Japan.
Eur J Dermatol. 2008 May-Jun;18(3):329-31. doi: 10.1684/ejd.2008.0398. Epub 2008 May 13.
We here report a 31-year-old male affected by a papillary tumor in his pubic region. At 26 years of age, he consulted a nearby clinic and was prescribed a topical cream. Although the condition was not relieved, he left the disease untreated. The gradually growing tumor adversely affected his quality of life, and he consulted another clinic, where he was referred to our hospital for surgery. The tumor had infiltrated the tissue at the base of the penis, but not the glans. After careful examination, we performed local excision of the tumor and a split-thickness skin graft. On pathological examination, elongation of the epidermis and koilocytes in the uppermost portion of the spinous layer were observed. Moreover, PCR examination confirmed the presence of human papillomavirus (HPV) type 11 in the tumor tissue. These findings supported a diagnosis of Buschke-Löwenstein tumor (BLT).
我们在此报告一名31岁男性，其耻骨区域患有乳头状肿瘤。26岁时，他前往附近诊所就诊，医生给他开了一种外用乳膏。尽管病情未缓解，但他未治疗该疾病。逐渐生长的肿瘤对他的生活质量产生了不利影响，他又咨询了另一家诊所，在那里他被转诊至我院进行手术。肿瘤已浸润阴茎根部组织，但未累及龟头。经过仔细检查，我们对肿瘤进行了局部切除并进行了分层皮片移植。病理检查发现，表皮延长，棘层最上部出现空泡细胞。此外，聚合酶链反应（PCR）检查证实肿瘤组织中存在11型人乳头瘤病毒（HPV）。这些发现支持Buschke-Löwenstein肿瘤（BLT）的诊断。
