Kudo O, Fujii H, Kondo I
Hinyokika Kiyo. 1984 Feb;30(2):217-22.
We report two cases of Buschke-Löwenstein Tumor on 39- and 55-year-old males. Both patients presented with mass and pain of glans penis. Pathological diagnosis of biopsy specimens were condyloma acuminatum in both cases. Bleomycin was not effective. Therefore, tumor resection in the first case and partial penectomy on second case were performed. Pathological examination revealed hyperkeratosis, acanthosis and downward growth of the prickle cell layer. But cellular atypia were not seen. Pathological diagnosis was Buschke-Löwenstein tumor. Our two patients are alive with no evidence of disease after 10 years. Pathological and clinical problems of Buschke-Löwenstein tumor were discussed by review of the literature.
我们报告了两例发生在39岁和55岁男性身上的Buschke-Löwenstein肿瘤。两名患者均表现为阴茎头肿物及疼痛。两例活检标本的病理诊断均为尖锐湿疣。博来霉素治疗无效。因此，第一例患者行肿瘤切除术，第二例患者行阴茎部分切除术。病理检查显示角化过度、棘层肥厚及棘细胞层向下生长。但未见细胞异型性。病理诊断为Buschke-Löwenstein肿瘤。我们的两名患者在10年后仍存活，无疾病证据。通过文献复习对Buschke-Löwenstein肿瘤的病理及临床问题进行了讨论。
