低风险产科患者沙眼衣原体的筛查
Screening for Chlamydia trachomatis in low-risk obstetric patients.
作者信息
Gribble R K, Ricci-Goodman J M, Berg R L
机构信息
Department of Obstetrics and Gynecology Marshfield Clinic, Marshfield, WI 54449, USA.
出版信息
Infect Dis Obstet Gynecol. 1994;1(4):177-81. doi: 10.1155/S1064744994000049.
OBJECTIVE
The purpose of this study was to evaluate the prevalence of Chlamydia trachomatis in our rural obstetric population and assess the appropriateness of selective vs. universal prenatal screening.
METHODS
Between April 1, 1991 and May 1, 1993, 1,587 patients were screened at their first prenatal visit using a C. trachomatis antigen test. Patients who were unmarried, younger than 20 years of age, or had a history of a previous sexually transmitted disease (STD) were classified as being at high risk for C. trachomatis. All others were considered low risk for C. trachomatis.
RESULTS
The overall prevalence of C. trachomatis was 2.0%. There was a significant difference (P < 0.001) in the 1,128 patients considered low risk [0.5%, 95% confidence interval (CI) 0.2-1.2] compared to the 459 patients with one or more identifiable risk factors (5.7%, 95% CI 3.7-8.2).
CONCLUSIONS
Routine prenatal screening for C. trachomatis in our population is not appropriate for low-risk patients.
目的
本研究旨在评估我国农村产科人群沙眼衣原体的患病率，并评估选择性与普遍性产前筛查的适宜性。
方法
在1991年4月1日至1993年5月1日期间，对1587例患者在首次产前检查时使用沙眼衣原体抗原检测进行筛查。未婚、年龄小于20岁或有既往性传播疾病（STD）史的患者被归类为沙眼衣原体高风险人群。所有其他患者被认为是沙眼衣原体低风险人群。
结果
沙眼衣原体的总体患病率为2.0%。与459例有一个或多个可识别风险因素的患者（5.7%，95%置信区间[CI]3.7 - 8.2）相比，1128例低风险患者（0.5%，95%CI 0.2 - 1.2）存在显著差异（P < 0.001）。
结论
对我国低风险患者进行沙眼衣原体常规产前筛查并不适宜。
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