Khassawneh Mohammad, Al-Balas Hassan
King Abdulla University Hospital, Jordan.
Pediatr Nephrol. 2008 Oct;23(10):1887-8. doi: 10.1007/s00467-008-0866-2. Epub 2008 May 15.
This is a case report of an association between morphine administration and occurrence of hydronephrosis with acute renal failure. This premature female infant born at 27 weeks of gestation had moderate hydronephrosis with acute renal impairment while receiving morphine infusion for pain management after chest-tube insertion. All these findings were reversed after stopping morphine and urinary catheterization. Follow-up renal ultrasound and voiding cystourethrogram showed resolution of hydronephrosis with no evidence of vesicoureteral reflux. Morphine is associated with reversible hydronephrosis and renal impairment in premature infants.
这是一篇关于吗啡给药与肾积水伴急性肾衰竭发生之间关联的病例报告。这名妊娠27周出生的早产女婴在插入胸管后接受吗啡输注以控制疼痛时,出现了中度肾积水和急性肾功能损害。停用吗啡并进行导尿后,所有这些症状均得到缓解。后续的肾脏超声和排尿性膀胱尿道造影显示肾积水已消退,且无膀胱输尿管反流迹象。吗啡与早产儿可逆性肾积水和肾功能损害有关。