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眼肌麻痹、共济失调和无反射综合征(费希尔综合征):9例临床分析

The syndrome of ophthalmoplegia, ataxia and areflexia (Fisher's syndrome): clinical analysis of 9 cases.

作者信息

Yip P K, Tsai S Y, Chen R C

机构信息

Department of Neurology, National Taiwan University Hospital, Taipei, R.O.C.

出版信息

Zhonghua Yi Xue Za Zhi (Taipei). 1991 Feb;47(2):126-32.

PMID:1848134
Abstract

From January 1976 through December 1988, 9 patients with clinical manifestations of the syndrome of ophthalmoplegia, ataxia and areflexia were diagnosed at National Taiwan University Hospital. Among them, 2 patients experienced recurrent attacks. A total of 12 attacks were recorded. Preceding symptoms of upper respiratory tract infection were noted in 9 out of 12 attacks. A spectrum of neuro-ophthalmological manifestations was observed. Most of these findings were probably secondary to central nervous system involvement. An elevation of protein level without pleocytosis was found in CSF examination of 6 attacks. Electrodiagnostic studies suggested large myelinated sensory fibers involvement as the major finding in 5 patients. A benign course in all 9 patients was noted. Special attention to nosological position and unusual features are also discussed.

摘要

1976年1月至1988年12月期间,台湾大学医院诊断出9例有眼肌麻痹、共济失调和无反射综合征临床表现的患者。其中,2例患者经历了复发发作。共记录到12次发作。12次发作中有9次发作前出现上呼吸道感染症状。观察到一系列神经眼科表现。这些发现大多可能继发于中枢神经系统受累。6次发作的脑脊液检查发现蛋白水平升高但无细胞增多。电诊断研究表明,5例患者的主要发现是大的有髓感觉纤维受累。9例患者病程均为良性。文中还讨论了对疾病分类位置和不寻常特征的特别关注。

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The syndrome of ophthalmoplegia, ataxia and areflexia (Fisher's syndrome): clinical analysis of 9 cases.眼肌麻痹、共济失调和无反射综合征(费希尔综合征):9例临床分析
Zhonghua Yi Xue Za Zhi (Taipei). 1991 Feb;47(2):126-32.
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The nosological position of Fisher's syndrome (ophthalmoplegia, ataxia and areflexia).费希尔综合征(眼肌麻痹、共济失调和无反射)的疾病分类地位。
J Neurol. 1983;229(1):33-44. doi: 10.1007/BF00313494.
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Detection of a central nervous system lesion in a patient with Fisher's syndrome.费舍尔综合征患者中枢神经系统病变的检测
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Correlation of 1a afferent conduction with the ataxia of Fisher syndrome.1a传入神经传导与费舍尔综合征共济失调的相关性。
Muscle Nerve. 1986 May;9(4):327-32. doi: 10.1002/mus.880090408.
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Electrophysiologic studies in Miller Fisher syndrome.米勒-费雪综合征的电生理研究
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[Auditory evoked potentials in Fisher's syndrome. A clinical case].[费希尔综合征的听觉诱发电位。1例临床病例]
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Neuro-ophthalmic manifestations of the syndrome of ophthalmoplegia, ataxia and areflexia. Observations on 20 patients.眼肌麻痹、共济失调和无反射综合征的神经眼科表现。对20例患者的观察
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Eye-movement abnormalities in ophthalmoplegia, ataxia, and areflexia (Fisher's syndrome).眼肌麻痹、共济失调和无反射(费希尔综合征)中的眼球运动异常。
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Syndrome of ophthalmoplegia, ataxia and areflexia.眼肌麻痹、共济失调和反射消失综合征
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