Edwards C N, Griffith S G, Hennis A J, Hambleton I R
Queen Elizabeth Hospital, Martindale's Road, St Michael, Bridgetown, Barbados, West Indies.
Inflamm Bowel Dis. 2008 Oct;14(10):1419-24. doi: 10.1002/ibd.20495.
The incidence of inflammatory bowel disease (IBD) may be lower among people of African descent than Caucasians. However, incidence studies among the former are uncommon and are often limited by incomplete case ascertainment or uncertainty about the size of the "at-risk" population.
We report the incidence and prevalence of IBD among people of African ancestry in Barbados from island-wide disease surveillance over a 25-year period beginning January 1980.
The annual incidence of IBD age standardized to the world population was 1.85 per 100,000 person-years (95% confidence interval [CI] 1.53-2.22) for ulcerative colitis (UC) and 0.70 per 100,000 person-years (0.51-0.95) for Crohn's disease (CD). These incidence rates increased to 2.09 and 0.76 when standardized to the US population. The UC incidence rate increased from 1.3 in 1980-1984 to 2.3 in 1995-1999, and decreased to 1.6 in 2000-2004. The CD incidence rate followed a similar trend, rising from 0.3 in 1980-1984 to 1.3 in 1990-1994 before decreasing to 0.6. IBD prevalence in December 2004 was 44.3 per 100,000 person-years (36.7-53.0) for UC and 16.7 per 100,000 person-years (12.2-22.4) for CD. In the island-nation of Barbados, with a population in 2000 of 270,000, we expect between 4.3 and 6.1 new cases of UC and between 1.5 and 2.6 new cases of CD each year.
The reported rates are generally lower than reported for European and North American Caucasians, and are similar to The French West Indies--the only other IBD disease register in the Caribbean.
非洲裔人群中炎症性肠病（IBD）的发病率可能低于白种人。然而，针对前者的发病率研究并不常见，且常因病例确定不完整或“高危”人群规模不确定而受到限制。
我们报告了自1980年1月起的25年期间，通过全岛疾病监测得出的巴巴多斯非洲裔人群中IBD的发病率和患病率。
以世界人口为标准进行年龄标准化后，溃疡性结肠炎（UC）的年发病率为每10万人年1.85例（95%置信区间[CI] 1.53 - 2.22），克罗恩病（CD）为每10万人年0.70例（0.51 - 0.95）。以美国人口为标准进行标准化后，这些发病率分别增至2.09和0.76。UC发病率从1980 - 1984年的1.3增至1995 - 1999年的2.3，随后在2000 - 2004年降至1.6。CD发病率也呈现类似趋势，从1980 - 1984年的0.3升至1990 - 1994年的1.3，之后降至0.6。2004年12月UC的患病率为每10万人年44.3例（36.7 - 53.0），CD为每10万人年16.7例（12.2 - 22.4）。在2000年人口为27万的岛国巴巴多斯，我们预计每年新增UC病例4.3至6.1例，新增CD病例1.5至2.6例。
报告的发病率总体低于欧洲和北美白种人的报告发病率，与法属西印度群岛（加勒比地区唯一的另一个IBD疾病登记处）的发病率相似。
