Mukhamed'ianova A Sh, Aznabaev R A, Aznabaeva L F
Vestn Oftalmol. 2008 Mar-Apr;124(2):39-42.
Polymerase chain reaction revealed Herpesviridae (Herpes simplex, Cytomegalovirus) in the lens substance in 46 patients operated on for age-related cataract. Thirty-two patients of them had age-related macular degeneration. Herpes simplex was found in 6 (18.8%) of the patients with age-related macular degeneration. At the same time there were signs of lacrimal fluid antiviral immunity imbalance with decreased IFN-gamma and TNF-alpha and increased IFN-alpha. The authors consider it advisable to perform antivirus treatment in patients with the above abnormality, preventing the active forms of herpetic infection.
聚合酶链反应显示,在46例因年龄相关性白内障接受手术的患者晶状体物质中发现了疱疹病毒科(单纯疱疹病毒、巨细胞病毒)。其中32例患者患有年龄相关性黄斑变性。在患有年龄相关性黄斑变性的患者中,6例(18.8%)发现了单纯疱疹病毒。同时,存在泪液抗病毒免疫失衡的迹象,γ干扰素和肿瘤坏死因子α减少,α干扰素增加。作者认为,对有上述异常的患者进行抗病毒治疗是可取的,以预防疱疹感染的活跃形式。